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Видео добавленное пользователем “nature video”
Laniakea: Our home supercluster
Superclusters – regions of space that are densely packed with galaxies – are the biggest structures in the Universe. But scientists have struggled to define exactly where one supercluster ends and another begins. Now, a team based in Hawaii has come up with a new technique that maps the Universe according to the flow of galaxies across space. Redrawing the boundaries of the cosmic map, they redefine our home supercluster and name it Laniakea, which means ‘immeasurable heaven’ in Hawaiian. Read the research paper: http://dx.doi.org/10.1038/nature13674 Read Nature's news story: http://www.nature.com/news/earth-s-new-address-solar-system-milky-way-laniakea-1.15819
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RNA interference (RNAi): by Nature Video
RNA interference (RNAi) is an important process, used by many different organisms to regulate the activity of genes. This animation explains how RNAi works and introduces the two main players: small interfering RNAs (siRNAs) and microRNAs (miRNAs). We take you on an audio-visual journey, diving into a cell to show how genes are transcribed to make messenger RNA (mRNA) and how RNAi can silence specific mRNAs to stop them from making proteins. The animation is based on the latest research, to give you an up-to-date view. If you'd like to know more about the structures and processes you see in this video, check out the accompanying slideshow: http://www.nature.com/nrg/multimedia/rnai/animation/index.html Sponsor message (May 2014): Dharmacon RNAi products are now part of GE Healthcare. Learn more at http://www.GELifeSciences.com/Dharmacon
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CRISPR: Gene editing and beyond
The CRISPR-Cas9 system has revolutionised gene-editing, but cutting DNA isn’t all it can do. From turning gene expression on and off to fluorescently tagging particular sequences, this animation explores some of the exciting possibilities of CRISPR. Download a poster on ‘The expanding CRISPR toolbox’ here: https://www.nature.com/posters/crisprtoolbox Produced with support from Dharmacon: https://www.dharmacon.com Nature has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors. Community contributed translations are enabled on this video. Nature is not responsible for the content of community-translated closed captions. 31st October 2017
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Lego Antikythera Mechanism
The Antikythera Mechanism: http://bit.ly/fm4oFK is the oldest known scientific computer, built in Greece at around 100 BCE. Lost for 2000 years, it was recovered from a shipwreck in 1901. But not until a century later was its purpose understood: an astronomical clock that determines the positions of celestial bodies with extraordinary precision. 

In 2010, we built a fully-functional replica out of Lego. 

Sponsored by Digital Science: http://www.digital-science.com/ a new division of Macmillan Publishers that provides technology solutions for researchers. Available under a CC-BY-3.0-Unported license. Antikythera Mechanism Research Project http://www.antikythera-mechanism.gr
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Immunology wars: Monoclonal antibodies
Our immune systems are at war with cancer. This animation reveals how monoclonal antibodies can act as valuable reinforcements to shore up our defences – and help battle cancer. You can find more on this topic at http://www.nature.com/milestones/antibodies Nature Research has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
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Tumour immunology and immunotherapy
This animation created by Nature Reviews Cancer and Nature Reviews Immunology illustrates how tumour cells are sensed and destroyed by cells of the immune system and how tumours can evolve to evade immune-mediated elimination. Scientists are developing new immunotherapies that help the immune system to ‘fight back’ — the animation explains how these exciting new drugs work. Nature has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors. See also: Nature Reviews Drug Discovery collection on Cancer immunotherapy: http://www.nature.com/nrd/collections/cancerimmuno Further reading: Focus on Tumour immunology & immunotherapy: http://www.nature.com/reviews/focus/tumourimmunology/index.html
Просмотров: 315447 nature video
Ion drive: The first flight
Researchers from MIT have flown a plane without moving parts for the first time. It is powered by an ‘ion drive’ which uses high powered electrodes to ionise and accelerate air particles, creating an ‘ionic wind’. This wind drove a 5m wide craft across a sports hall. Unlike the ion drives which have powered space craft for decades, this new drive uses air as the accelerant. The researchers say it could power silent drones. Read the original research paper: https://doi.org/10.1038/s41586-018-0707-9 Read Nature’s Editorial which also raises possible concerns about how a silent drone might be used: https://doi.org/10.1038/d41586-018-07477-9
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Method of the Year 2010: Optogenetics - by Nature Video
This video shows how scientists can control the behaviour of cells simply by switching on a light. The technique, known as optogenetics, is teaching us about everything from how we wake up to how we learn. That's why Nature Methods has named optogenetics as its Method of the Year 2010. Read more at www.nature.com/nmeth/focus/moy2010/index.html
Просмотров: 217620 nature video
Have you ever seen an atom?
Scientists at the University of California Los Angeles have found a way to create stunningly detailed 3D reconstructing of platinum nanoparticles at an atomic scale. These are being used to study tiny structural irregularities called dislocations. Read the paper here: http://dx.doi.org/10.1038/nature12009
Просмотров: 7881235 nature video
Immunology in the Gut Mucosa
The gut mucosa hosts the body's largest population of immune cells. Nature Immunology in collaboration with Arkitek Studios have produced an animation unravelling the complexities of mucosal immunology in health and disease. Nature Immunology homepage: http://www.nature.com/ni/index.html Nature has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
Просмотров: 350562 nature video
See-through brains
Scientists have come up with a way to make whole brains transparent, so they can be labelled with molecular markers and imaged using a light microscope. The technique, called CLARITY, enabled its creators to produce the detailed 3D visualisations you see in this video. It works in mouse brains and human brains; here the team use it to look into the brain of a 7-year-old boy who had autism. Original research paper: http://dx.doi.org/10.1038/nature12107 Nature News story: http://www.nature.com/news/see-through-brains-clarify-connections-1.12768
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How to see around corners
This video shows how scientists at the MIT Media Lab (www.media.mit.edu/) reconstruct a hidden object using scattered laser light. Future applications may include seeing in dangerous or inaccessible locations, such as inside machinery with moving parts, or in highly contaminated areas. Read the original research: http://www.nature.com/ncomms/journal/v3/n3/full/ncomms1747.html Check out the researchers' project URL: http://cornar.info And first author's web page http://web.mit.edu/~velten/www/ Animations by Sam Woolf: http://www.samwoolf.net/ Music by Jay Marsh http://www.jaymarshmusic.com/
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The Barefoot Professor: by Nature Video
Harvard professor Daniel Lieberman has ditched his trainers and started running barefoot. His research shows that barefoot runners, who tend to land on their fore-foot, generate less impact shock than runners in sports shoes who land heel first. This makes barefoot running comfortable and could minimize running-related injuries. Read more here http://www.nature.com/news/2010/100126/full/news.2010.36.html and find the original research here: http://dx.doi.org/10.1038/nature08723
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Tiny treasure: The future of nano-gold
Lumps of gold moulded into rings, coins and ingots have been highly prized for millennia. But recently, scientists have realised that tiny pieces of this precious metal – far too small to be seen by the naked eye - could also become a valued commodity. In labs around the world, gold nanoparticles are being tested as components in technology and medicines. See how gold could be used to kill cancer cells, improve the efficiency of solar cells and catalyse chemical reactions. Read more about the nanotechnology applications of gold: http://www.nature.com/nature/outlook/gold_2013/ Nature has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
Просмотров: 96119 nature video
Method of the Year 2011: Gene-editing nucleases - by Nature Video
Gene-editing nucleases can make targeted and precise changes to an organism's genome. This has opened up new possibilities for the study of gene function, as well as the treatment of disease. While gene-editing nucleases have been in use since the mid-1990s, in the form of zinc finger nucleases, the more recent discovery of TALENs (transcriptor-like effector nucleases) has created new interest. In this video, Nature Methods technology editor Monya Baker explains how gene-editing nucleases work and why they were chosen as Nature Methods 'Method of the Year' for 2011. More on the 2011 'Method of the Year' here: http://www.nature.com/nmeth/focus/moy2011/
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Innate lymphoid cells
Along with the skin, the gut mucosa represents the first line of defense against environmental factors. In the gut mucosa, a recently discovered type of lymphocytes called innate lymphoid cells (ILCs) maintain tissue homeostasis, orchestrate tolerance to food or commensal bacteria and contribute to immune responses to pathogens. This Nature Video shows the complexity of ILC biology in the gut mucosa at steady state and disease. Read more about ILCs here: http://www.nature.com/ni/focus/ILC Nature has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
Просмотров: 45520 nature video
Inside Alzheimer’s disease
Our understanding of Alzheimer’s disease has come along way in the last century. In this animation, Nature Neuroscience takes us inside the brain to explore the cells, molecules and mechanisms involved in the onset and progression of this devastating condition - from the latest advances to the remaining gaps in our scientific knowledge. Nature Neuroscience has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
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Immunology of the Lung
Our lungs bring in vital oxygen and expel carbon dioxide. But they’re also an important immune site. They filter the air we breathe, repulsing invaders and repairing injury. But sometimes these powerful immune responses overreact, causing diseases such as asthma. Go to the Nature Immunology homepage: http://www.nature.com/ni/index.html Nature has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
Просмотров: 81170 nature video
Inside ALS: The neurons behind the disease
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that mainly affects the nerve cells (neurons), which control muscle movement. As the motor neurons degenerate, they stop sending signals to the muscles, causing progressive muscle weakness and — ultimately — death. This animation focuses on the mechanisms within the motor neurons that cause them to degenerate. By understanding these mechanisms, researchers hope to one day find a cure for ALS. To learn more about ALS, check out the Primer: https://www.nature.com/articles/nrdp201771 and the PrimeView: https://www.nature.com/articles/nrdp201772 Nature Research has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
Просмотров: 54515 nature video
Immunology wars: A billion antibodies
Our bodies can create billions of antibodies to fight off billions of potential diseases. But how do our immune systems turn a limited number of genes into such an incredible diversity of antibody proteins? You can find more on this topic at http://www.nature.com/milestones/antibodies Nature Research has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
Просмотров: 42596 nature video
Paper and string: the DIY centrifuge
A centrifuge is a vital piece of kit for hospitals and labs across the world. But what if you could make one out of paper and string? The so-called ‘paperfuge’ is the cheapest and fastest hand-spun centrifuge ever designed — and it can reach speeds of up to 125,000 revolutions per minute. Nature Video reveals how this invention will allow basic diagnostic tests in areas without laboratory resources or electricity. The paper has been published in Nature Biomedical Engineering. Read it here: http://www.nature.com/articles/s41551-016-0009
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Mitochondrial diseases
Mitochondrial diseases are a group of disorders caused by genetic mutations. In this animation, Nature Video finds out how these diseases arise, and how new techniques can stop them being passed on from mother to child. To learn more about mitochondrial diseases, check out the Primer: http://www.nature.com/articles/nrdp201680 and the PrimeView: http://www.nature.com/articles/nrdp201681
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Cat domestication: From farms to sofas
Years before they conquered the Internet, cats colonized our sofas. But they haven’t spent the last ten thousand years just snoozing. A new study reveals that tamed cats swept through Eurasia and Africa carried by early farmers, ancient mariners and even Vikings. The researchers analysed DNA from over 200 cat remains and found that farmers in the Near East were probably the first people to successfully tame wild cats 9,000 years ago, before a second wave of cat domestication a few thousand years later in ancient Egypt. Read the original research paper in Nature Ecology & Evolution: http://dx.doi.org/10.1038/s41559-017-0139 Nature news story about the study: http://www.nature.com/news/how-cats-conquered-the-world-and-a-few-viking-ships-1.20643
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The computer that mastered Go
Go is an ancient Chinese board game, often viewed as the game computers could never play. Now researchers from Google-owned company DeepMind have proven the naysayers wrong, creating an artificial intelligence - called AlphaGo – which has beaten a professional Go player for the first time. In this Nature Video, we go behind the scenes to learn about the game, the programme and what this means for the future of AI. Read the original research paper at https://www.nature.com/nature/journal/v529/n7587/full/nature16961.html
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Monkeys can make stone tools too
Stone flakes made by capuchin monkeys look remarkably similar to stone tools made by early humans 2-3 million years ago, raising questions about the archaeological record. Read more in this news story: http://www.nature.com/news/monkey-tools-raise-questions-over-human-archaeological-record-1.20816 Read the original research paper: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature20112.html
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The secret physics of dandelion seeds
Every child knows that blowing on a dandelion clock will send its seeds floating off into the air. But physicists wanted to know more. How does an individual seed manage to maintain such stable flight? Researchers at the University of Edinburgh studied the fluid dynamics of air flow around the seed and discovered a completely new type of flight. It’s based on a previously unknown kind of vortex which may even be common in the plant and animal kingdoms, now that we know where to look. Read more on this from Nature News: https://www.nature.com/articles/d41586-018-07084-8 And you can find the original research paper here: https://www.nature.com/articles/s41586-018-0604-2 17 October 2018
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The nerve bypass: how to move a paralysed hand
After a broken neck left him quadriplegic, Ian Burkhart was told he would never be able to use his hands. Now he can grasp a bottle and pick up a credit card by using a computer plugged directly into his brain. Special software is able to decode his thoughts and convert them into electrical signals in his hand, bypassing the damaged nerves in his spine. Now Ian has regained an amazing degree of control over his hand, each movement stimulated by his own thoughts. The research was carried out at The Ohio State University and Battelle Memorial Institute. Chad Bouton was based at Battelle for the duration of the project. He has since moved to the Feinstein Institute. Read the paper here: http://www.nature.com/doifinder/10.1038/nature17435 And for more information check out the news article here: http://www.nature.com/news/first-paralysed-person-to-be-reanimated-offers-neuroscience-insights-1.19749 13th April 2016
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Huntington Disease
Huntington disease is caused by a mutation in the HTT gene. Understanding how the mutation causes neurodegeneration might help researchers develop treatments that protect brain function. This animation describes the genetic defect that underlies Huntington disease. Created by the editors at Nature Reviews Disease Primers. Learn more about Huntington disease with the Primer http://dx.doi.org/10.1038/nrdp.2015.5 and PrimeView http://go.nature.com/hPMENh
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The exoplanet next door
*NOTE* This video contains an error. At 0:54 an animation representing the radial velocity method for finding exoplanets is incorrect. Here is a link to a correct representation https://www.eso.org/public/unitedkingdom/videos/eso1035g/ Astronomers have discovered evidence of a small, rocky planet orbiting our nearest star – and it may even be a bit like Earth. Nobody knows whether the planet, called Proxima b, could ever sustain life. The little planet orbits our sun’s nearest neighbouring star, Proxima Centauri, making it the closest exoplanet ever found.   Read the paper here: http://www.nature.com/doifinder/10.1038/nature19106 24th August 2016
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Creating Gollum
This month sees the release of the second film in The Hobbit trilogy: The Desolation of Smaug. Perhaps the most well-known of its characters is Gollum, a mysterious cave-dwelling creature corrupted by the power of the ring. His digital character was created by New Zealand-based visual effects company Weta Digital. In this Nature Video we go behind the scenes with Weta's Senior Visual Effects Supervisor, Joe Letteri, who reveals the technology they used to make Gollum's eyes, skin and movements look believable. Joe Letteri has written a feature on the development of Weta Digital's animations for Nature. Read it here: http://www.nature.com/doifinder/10.1038/504214a
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Hobbit histories: the origins of Homo floresiensis
The origins of the species known as 'the hobbit' - a human relative only a little over a metre tall - have been debated ever since its discovery in 2004. Now new fossils may reveal the ancestors of this strange species and help us to understand its history. Read more from nature news here: http://www.nature.com/uidfinder/10.1038/534164a Find the paper on the new fossils here: http://www.nature.com/doifinder/10.1038/nature17999 And a second paper here covers the age and context of the fossils: http://www.nature.com/doifinder/10.1038/nature17663 8th June 2016
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Paralysed woman moves robot with her mind - by Nature Video
Cathy Hutchinson has been unable to move her own arms or legs for 15 years. But using the most advanced brain-machine interface ever developed, she can steer a robotic arm towards a bottle, pick it up, and drink her morning coffee. The interface includes a sensor implanted in Cathy's brain, which 'reads' her thoughts, and a decoder, which turns her thoughts into instructions for the robotic arm. In this video, watch Cathy control the arm and hear from the team behind the pioneering study. The original research paper is here: http://www.nature.com/nature/journal/v485/n7398/full/nature11076.html
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Skeleton uncovered at ancient Antikythera shipwreck
The famous shipwreck that brought us the mysterious Antikythera mechanism has revealed a new secret: a two-thousand-year-old human skeleton. The team hopes to extract DNA from the skull - a feat never attempted before on bones this old that have been underwater. Read Nature's news article here: http://www.nature.com/news/human-skeleton-found-on-famed-antikythera-shipwreck-1.20632 Read about the Return to Antikythera project here: http://antikythera.whoi.edu/ 19th September 2016
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Every Space Shuttle ever launched, in order
NASA's pioneering reusable Space Transportation System (STS) was in operation for 30 years. 355 men and women flew on the five Space Shuttles over 135 missions. This video shows all of them. http://www.nature.com/spaceshuttle Soundtrack: 'PX3' and 'Retreat! Retreat!' by 65daysofstatic. *Film previously titled "Space Shuttle United -- by Nature Video" updated 08/01/2018
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Targeting tumours: Challenges of antibody-drug conjugates
Treating cancer requires aggressive but targeted therapy. Some cancer drugs are too toxic because they damage healthy cells as well as tumor cells. So researchers are trying to develop ways to make sure drugs only target the right cells. One solution is to attach drugs to antibodies specific to a protein expressed on tumour cells. These drugs are called antibody-drug conjugates (ADCs). More than two dozen ADCs are currently being used in the clinic to treat diseases like Hodgkin's lymphoma and breast cancer, and researchers are developing many more. But it's taken decades to find the right combination of drug, antibody target and linker, and then make sure the right amount of ADC hits the tumor. In this 3D animation, produced by Nature Biotechnology, we hear about these challenges and the ways ADCs target cells. This content is editorially independent of sponsors. Animation by Nucleus Inc.. www.nucleuscatalog.com/home
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Immunology of the rheumatoid joint
Rheumatoid arthritis is an inflammatory disease that mainly affects the joints in which the body's immune system attacks its own tissues. This animation produced by Nature Reviews Immunology and Nature Reviews Rheumatology guides us through the immune pathways involved in the disease, from the first signs of self-reactive immune cells to joint damage and other symptoms, and highlights opportunities for new treatments. Nature Reviews Immunology (http://www.nature.com/nri) and Nature Reviews Rheumatology (http://www.nature.com/nrrheum) have full responsibility for all editorial content. This content is editorially independent of sponsors.
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Retinal repair: Bringing stem cells into focus
The retina is the eye’s most sophisticated component. Researchers are developing techniques to recreate retinal tissues — and even entire retinas — in the lab. These complex structures can then be transplanted into patients and could help to restore lost vision in people affected by diseases such as age-related macular degeneration. Read more at https://www.nature.com/collections/yvwsxqgynv This Nature Video is editorially independent. It is produced with third party financial support. Read more about Supported Content here: https://partnerships.nature.com/commercial-content-at-nature-research/
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Psoriasis and beyond: targeting the IL-17 pathway
Psoriasis is a chronic inflammatory skin disorder that affects about 2-3% of the population. It is triggered by the immune system, and new insights into the immune processes have thrown up a number of exciting drug targets. This Nature Reviews Drug Discovery animation explores how the immune system goes awry in psoriasis and illustrates how agents that target the cytokine interleukin 17, or other players in the same pathway, are being developed into novel therapies for psoriasis.
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Gentle giants of the Cambrian
More than 500 million years ago in the Cambrian period there was an explosion of animal life. The top predators were from a group called the Anomalocarids, the largest animals of their day. But now, a new fossil suggests that not all the Anomalocarids were the fearsome killing machines scientists once thought. At least one, it seems, evolved into a gentle giant. Read the paper: http://www.nature.com/nature/journal/v507/n7493/full/nature13010.html Cambrian animations: http://burgess-shale.rom.on.ca/
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Repairing the cornea: let there be sight
The cornea is our window onto the world, letting light into our eyes, and it must be kept in perfect condition. Damage to the cornea and the vital ‘limbal’ cells that surround it can have severe consequences, and can ultimately lead to blindness. In this animation we explore how doctors treat such problems and how regenerative medicine is helping in the battle to restore sight. Read the full Nature Outline: http://www.nature.com/nature/outline/corneal-repair/ Nature Research has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
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Immunology in the skin
The skin is the body's main barrier against physical insults and microbial pathogens. Diverse and functionally specialized subsets of immune cells in the skin sense and respond to infection or various barrier breaches to activate an immune response and eventually, return to homeostasis. However, deregulated immune responses can also cause skin disorders, such as psoriasis. This Nature Video introduces the environment and key participants in skin immunity during steady-state and disease. Nature has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
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Repairing the eardrum: The sound of self-healing
Ruptured eardrums are relatively common. Fortunately, small tears usually heal by themselves. But some large tears need to be repaired by a surgeon. This animation shows how a new tissue engineering technique could make that process much easier and cheaper. The technique uses a scaffold and growth factor to stimulate the eardrum’s own cells to grow over the tear. For a poster on this subject go to: http://www.nature.com/nature/outline/eardrum-regeneration Nature Research has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors.
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A mini, magnetic, all-terrain robot
A tiny robot is making leaps and bounds for small-scale locomotion. This soft robot really can walk the walk, as well as being able to roll, jump and swim. This could help it navigate the surprisingly tough terrain inside a human body. Read more: https://www.nature.com/articles/nature25443 1st February 2018
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The Story of You: ENCODE and the human genome
Ever since a monk called Mendel started breeding pea plants we've been learning about our genomes. In 1953, Watson, Crick and Franklin described the structure of the molecule that makes up our genomes: the DNA double helix. Then, in 2001, scientists wrote down the entire 3-billion letter code contained in the average human genome. Now they're trying to interpret that code; to work out how it's used to make different types of cells and different people. The ENCODE project, as it's called, is the latest chapter in the story of you. To read the ENCODE research papers and more, visit http://www.nature.com/ENCODE
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A virtual time machine for Venice
The State Archives of Venice contain records stretching back over a thousand years. The vast collection of maps, images and other documents provide an incredibly detailed look into Venetian history. This could be used to create a kind of virtual time machine for historians and the public to explore the city. Read the feature here: http://www.nature.com/news/the-time-machine-reconstructing-ancient-venice-s-social-networks-1.22147 And find out more about the project at: http://vtm.epfl.ch   14th June 2017
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Gravitational waves: A three minute guide
It's almost exactly a century since Einstein first predicted the existence of gravitational waves. In this Nature Video we find out what they are, and how scientists are searching for them, in an attempt to prove Einstein right.
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Charting culture
This animation distils hundreds of years of culture into just five minutes. A team of historians and scientists wanted to map cultural mobility, so they tracked the births and deaths of notable individuals like David, King of Israel, and Leonardo da Vinci, from 600 BC to the present day. Using them as a proxy for skills and ideas, their map reveals intellectual hotspots and tracks how empires rise and crumble The information comes from Freebase, a Google-owned database of well-known people and places, and other catalogues of notable individuals. The visualization was created by Maximilian Schich (University of Texas at Dallas) and Mauro Martino (IBM). Read Nature's news story: http://www.nature.com/news/1.15650 Find the research paper in Science: http://www.sciencemag.org/lookup/doi/10.1126/science.1240064
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Hallucigenia: The worm with the missing head
The remains of an ancient worm species called ‘Hallucigenia' were so bizarre looking that scientists originally reconstructed it upside down and back to front. Now Martin Smith reveals the most complete picture so far of this peculiar marine worm. Read the Nature paper ‘Hallucigenia’s head and the pharyngeal armature of early ecdysozoans’ at www.nature.com/doifinder/10.1038/nature14573 Find out more about Hallucigenia and other finds from the Burgess Shale at www.burgess-shale.rom.on.ca 24th June 2015
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The evolution of oral anticoagulants
Blood clots can form where they aren't needed, and cause serious medical problems. This animation produced by Nature Reviews Cardiology and Nature Reviews Drug Discovery explores progress in the development of oral anticoagulants that target components of the blood coagulation cascade to inhibit blood clotting in high-risk patients, as well as recent advances with antidotes to reverse the effects of oral anticoagulants when necessary. Nature Reviews Cardiology (http://www.nature.com/nrcardio) and Nature Reviews Drug Discovery (http://www.nature.com/nrd) have full responsibility for all editorial content. This content is editorially independent of sponsors. See also: Nature Reviews Cardiology poster on 'Anticoagulant drugs' available at http://www.nature.com/nrcardio/posters/anticoagulation/index.html
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The first Americans: Clues to an ancient migration
An archaeological site in California may have opened up a whole new chapter in the history of humans in the Americas. Researchers claim the site shows evidence of humans interacting with the bones of a mastodon, an ice age relative of elephants and mammoths. New dating suggests the site may be 130,000 years old – 100,000 years earlier than the accepted date for the first human colonisation of the Americas. Read the paper here: http://nature.com/articles/doi:10.1038/nature22065 And a News & Views article here: http://www.nature.com/nature/journal/v544/n7651/full/544420a.html 26th April 2017
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