5-MeO-MiPT is a psychedelic in the tryptamine class. It's uncommon relative to LSD and psilocin, but it has been used for a couple of decades. It's not a very visual substance at common doses. Instead, it's known for producing greater tactile, bodily, and sexual effects than other psychedelics.
It's part of the research chemical market and has been sold as itself and as a component of branded products.
TDC Overview Page (with references): https://thedrugclassroom.com/video/5-meo-mipt/
Reddit discussion: https://www.reddit.com/r/TheDrugClassroom/comments/8iwb1n/5meomipt_what_we_know/
Thank you to Ben/BronzeManul(http://thesteppe.co/) for general help with the video, in particular the chemistry section and the chemical structure images.
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The Drug Classroom (TDC) is dedicated to providing the type of drug education everyone should have. Drugs are never going to leave our society and there has never been a society free from drugs.
Therefore, it only makes sense to provide real education free from propaganda.
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It seems YouTube’s strike/restriction system is still overstepping its bounds. After receiving and beating a few strikes that threatened to shut down the channel in February/March, I thought this issue had been resolved. I was wrong.
Yesterday I received a new strike, removing my ability to livestream. If I get another then TDC’s ability to upload will temporarily be removed.
None of TDC’s content seems to be in violation of the guidelines, but because it’s about drugs, the videos are still being removed.
I believe TDC will remain on YouTube, though even if something were to happen it would not go away, I’d simply move to other platforms. The most important thing for ensuring the sustainability of TDC is funding, which exclusively comes from donations since TDC doesn’t use ads or sponsors.
If you want to help, you can find all of the donation options here: https://thedrugclassroom.com/support/
I am very angry at how they are treating you. Let us help you all, tell us what to do. There is enough of us watching now that the viewers of these drug education, harm reduction video's can actually do something about it.
The Drug Classroom Your channel is simply educational and I appreciate your work. YouTube is getting worse by the day. I've noticed my suggestion list is very different lately. Anything with drugs,guns, war, or even right of center is nowhere to be seen. Also your channel automatically goes to the bottom of my subscription list. I'm close to done with YouTube.
You should do a video on isotretinoin. Not a psychoactive compound, which is what you usually cover, but a drug with a relatively high-risk safety profile whose mechanism of action is only recently being unveiled.
Hi Seth! I recently became a subscriber and am impressed with how thorough and objective you are in your explanations. I also find it interesting that you have so much information on substances with a very short history of use. Have you thought about making a video on ephenidine?
Can you do 4-aco-dmt and touch on the fact then when ROA bipasses the liver ( IV, rectal, or vaporized as a free base) it has instantaneous effects on its own before its turned into psilocin, effects much different to psilocin and more reminiscent of dmt because of the rush and visuals. I can confirm this to be true, i did more than just read this on a forum if you know what i mean.
Andrew Mastrantoni yeah, even with my experience I thought the only person that I’d be comfortable doing it with (tripsitter, he didn’t do it) was my older brother. I didn’t think even my friends would hold up in the salvia trip, but I knew I’d always trust my brother if I started freaking out. Definitely was a unique experience nonetheless
Andrew Mastrantoni I’ve done it and I’ve also done 10 tabs of acid and breakthrough amounts of dmt. I’ve been way too fucked up on a dozen drugs. I don’t need help researching it, I can (and did) do that myself. Again, I just like his videos.
Tramadol not only acts as an opioid, but in addition to that acts as a SNRI (iirc tramadol itself is a stronger SSRI and its metabolite is more of an NRI) so if you combine it with other drugs that act on the serotonin system you risk serotonin toxicity, which in the worst case could be deadly
Since you know a lot about medications I could really use your help last week I thought I was having a lot of symptoms that are like serotonin syndrome. I stopped some of my meds to see if I would feel better this is what I'm on Seroquel 400 mg lithium 300 mg twice a day Wellbutrin 450mg well so adderal 40 mg long-acting clonidine 0.1 Suboxone 24 mg metformin 5oomg lisinopril.hydrochloro 10..12.5 tabs Gabapentin 300 mg 3 times a day..baclofen 10 mg three times a day....pantoporazole 40mg and for breathing Brio and lncruse... if you can can you tell me if that would cause serotonin syndrome?
To say that one drug is "better" than another... it is subjective. It depends on what a person is going for. To say that lydocaine is better than acetaminophen, is just comparing apples to oranges. They both do a good job for what they are intended for. You wouldn't use lydocaine for a headache.
Matěj Novák I've took it for a week for 4 weeks once I didn't get any brain zaps or depression I just kinda felt tierd that was about it I didn't feel any difference but then again its inside your brain how are you gonna truly know if you can't feel it so I would say the 3 month guide line is the best as that is what I stick to now but his answer may be different as the 3 month rule originally came from Ann shlugin about the magic its nothing to do with neurotoxicity
Matěj Novák Afaik, that’s not supported by any science. You should watch the MDMA video on this channel. It has some of the answers you’re looking for as far as the current scientific understanding of MDMA use goes, although I don’t think it has any information about Seth’s personal use.
I'm actualy not... but i was asking him... because a lot of people say the 3 month rule is still kinda wrong... That mdma should be taken at most twice a year if you want to keep neurotoxicity from destroying your brain
1 month for serotonin reupake but 3 months to keep the so called " magic " and just a heads up IG you ever get a dark brown rock of MDMA give it a acetone wash it takes out impurities and makes there be almost 0 comedown expect feeling tired I don't if its scientifically backed but I found it to be better and to stick to common dosages don't go above 200-220mg in one sitting/night and drink 250-500ml of water every 1 hour I know you didn't ask for all this but you seem new to MDMA so here is some tips
The only 5-subbed tryptamine I tried was bufotenine when I took a fat line of Yopo seeds during the pharmahuasca trip and got similar effects to that described in the video-not much visual enchantment but it felt really euphoric and lightened the bizzare mood of DMT trip.I guess the effects are pretty similar in 5-subbs except for 5-Meo-DMT,by effect description it looks more like salvia
I cannot understand why these people are not supporting this channel?? I find your channel Educational. I personally feel like you are helping people understand what these drugs are and what they can do to a person's health.Most of the other people complain and carry on about the opioid problem but they really don't educate you on all the side effects and all of the problems it Truly causes.They just throw people in jail and that is that.People need help and understanding after all this is a disease. They don't need to be treated like they are a piece of trash or a door mat that isn't the solution at all.There is enought igornance in the world.We need way more education in this world and alot more understanding.PLEASE LET'S KEEP THIS EDUCATIONAL CHANNEL GOING. Keep up the GREAT WORK YOU ARE DOING.. GOD BLESS YOU. SINCERELY....
The main ingredient from both of those seeds is bufotenine,though it is said that Yopo seeds also contain DMT and 5-Meo dmt but probably in small amounts.Also I don't think you can smoke them and get effects unless you extracted pure Bufo from those seeds and then smoke it
From wiki:Several small-scale studies (involving 15 or fewer test subjects) conducted in the 1950s and 1960s reported that adrenochrome triggered psychotic reactions such as thought disorder, derealization, and euphoria. Researchers Abram Hoffer and Humphry Osmond claimed that adrenochrome is a neurotoxic, psychotomimetic substance and may play a role in schizophrenia and other mental illnesses.
Could this be what Substance D is based of?
Adrenochrome isn't significantly active, (correct me if I'm wrong) but if I remember correctly, Rick Strassman mentioned Adrenochrome and it's potential relationship to the endogenous production of DMT in his book, "DMT: The Spirit Molecule". Pretty interesting stuff.
Antidepressants are medications that can help relieve symptoms of depression, social anxiety disorder, anxiety disorders, seasonal affective disorder, and dysthymia, or mild chronic depression, as well as other conditions.
They aim to correct chemical imbalances of neurotransmitters in the brain that are believed to be responsible for changes in mood and behavior.
Depression Medications (Antidepressants)
These are the most commonly prescribed type of antidepressant.
Serotonin and noradrenaline reuptake inhibitors (SNRIs) are used to treat major depression, mood disorders, and possibly but less commonly attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), anxiety disorders, menopausal symptoms, fibromyalgia, and chronic neuropathic pain.
SNRIs raise levels of serotonin and norepinephrine, two neurotransmitters in the brain that play a key role in stabilizing mood.
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants. They are effective in treating depression, and they have fewer side effects than the other antidepressants.
SSRIs block the reuptake, or absorption, of serotonin in the brain. This makes it easier for the brain cells to receive and send messages, resulting in better and more stable moods.
They are called "selective" because they mainly seem to affect serotonin, and not the other neurotransmitters.