A very complex matter. First off, Depression is a very loose term covering several mental disorders. I don’t think it has ever been proved that lack of serotonin is the problem. For example, is bi polar caused by lack of serotonin. There is a newer theory linking over and under methylation with mental problems. SSRIs only work well for some people so why not all. There is a strong genetic component. SSRI s are anti cholingenic meaning they interfere with several chemical messaging functions. Loss of libido is a major one and can be distressing in itself. The first major anti psychotic drug was only discovered in the 1950s when it was given to try and ameliorate TB. Scientists still don’t really know why it worked but there again, side effects were awful.
I started taking SSRI's 6 weeks ago and already the difference is astonishing! I should've done it years ago. The mental fog I've had all my life is gone, I can think quickly and concisely for the first time and I'm no longer perpetually depressed! Result! This changes everything.
It helps to know what's going on now in my head so thank you so much for posting this!
Not sure what your education level cause I’m hoping you have a MD or youve taken pharmacology classes but Permanent memory is very common. Only people with adhd or high intelligence can notice when medication is mentally handicapping you. It’s just like weed, it clouds your mind and effects short and long term memory also causes slight permanent memory loss like loss of vocabulary, harder to retain and learn new things, and you’ll forget why you walked in a room a lot. However SSRIs are the worst, depressed people are mentally fogged and don’t realize what ssris do, when i was on lexapro my grades when from As to failing out almost and i did my research and found out lexapro causes your my brain to permanently change only from one pill. It changes your brain chemistry forever and you’ll, never be the same mentally ill drop links later but the answer are on the internet. Basicallyl the effect of lexapro was i was studying for bio/organic chemistry and i would start reading my book and i would read the same page 20 times and everytime i had no idea what i just read almost like if they weren’t words anymore to me a]after that i immediately stopped cold turkey and week later i was back to my normal self almost, by that i mean I’ve never got back to my former mental state, I’m slower, takes me longer to learn, and i lost a lot of intelligence and it gave me depression thinking how could a pill my doctor gave me ruin my cognition forever. I’ve been on lexapro, Wellbutrin, vyvanse, and CBD. I’m also a psychiatric nurse practitioner which is equivalent to a psychiatrist meaning i prescribed medication to people and give therapy. I’ve learned about every kind of medication and I’ve even been on most of the major ones which gives me personal experiences that helps me give the best treatment for my patients. So basically be careful of the medication you take. And before you take them makes you do your research, never just listen to what your doctor tells you about what they are prescribing without being informed and taking into account the pros and cons.
Funny you say that. I've never taken ssris before and I have been going through the same thing with having to read a page over and over again. Ssris aren't terrible to take if they work for somebody. It takes time to find the right combination. And they might not go with your body chemistry, but that isn't the medications fault. Everyone's body is made up differently.
By what you said about Jack being lucky to have an SSRI, or whatever, you make it sound like medication is the answer to all depression. What you should have said was if therapy wasn't helpful enough, *then* an SSRI is one of the other possibly effective treatments. For many cases of depression, medication *should not* be the first thing you try.
There are a few factors in treating social anxiety at home. One place I discovered which succeeds in merging these is Kevs Control Plan (google it if you're interested) definately the no.1 resource that I've heard of. look at the amazing info .
Great video. I've just began taking SSRI's and they've helped a lot. It seems like most commenters who've taken or take SSRI's vouch for them while those who've never taken them think they're just a plot by big pharma to make money.
aditya thakur I hate them. Mine stopped working after a year and now it’s been a year since I’ve stopped taking them and I STILL get withdrawal symptoms. I’ll probably only take them again when I’m like 80 and everyone I love has passed away.
But I hope they work for you!
Yoeri Hengeveld your right confidence and self esteem are they key....everyone feels low, though if one has enough of the above your able to bat that negativity away, and not not hold onto that vicious circle of self doubt and Depression
I didn't have a major depression but the psychiatrist gave vortioxetine to me. People Could you give me details about your time with it, please? Did you have some of the symptoms I have been experiencing in the last month and a half? Ive been on it for 3 months, and I dont feel good; sometimes I feel sad (I never felt sad), I have crazy ideas like I can't scape from myself or the future, I feel like my future is ruined, sometimes I feel nothing at all: any emotion. Anxiety sometimes appears. Do you think is the med? After you stopped it, did you feel better later? Thank you for your time people.
There are some side effects to SSRI's, and they are not for everyone. SSRI's may of course help if serotonin is low. According to "WRI," about 38% of depressives have lower than normal levels of serotonin, and that is why they tend to get depressed. In this case, SSRI's may help but still have side effects. In this case, other alternatives like nutritive support for underlying imbalances causing the problem can be at least as effective. Given to the wrong people, however, SSRI's can have fatal consequences (read the PDF "A Proposal for Prevention of School Shootings" - not directly related to this article of course but...): https://www.vitacure.me/blogs/news/difference-undermethylated-vs-overmethylated-symptoms
Seratonin is what LSD and PCP mimick, high levels of seratonin can and do cause hallucintaions and there in is your cause for the wide spread mass shootings taking place in the United States. These drugs do far more evil than good, lets get busy holding the government and the drug makers accountable for these mass shootings, guns are not responsible, drug manufacturers and your own government are the cause for your dead children. Sue the drugs makers, we need to stop making excuses. Everyone of these shooters was on one or more of these SSRI drugs when they murdered other people... this is the only common factor that they all had, yet the media ignores it, the libtards ignore it, and your government ignores it.
Yea it sounds good but All ssri’s eventually stop working after three months leaving you with nothing but side effects and that’s when the doctor suggests a different but stronger anti depressant and possibly a second medication to counter act the side effects you feel from the last medication then eventually that medication stops working then it’s back to the doctor for another medication upgrade. How do you think big pharm company’s make money
So this is like the same as for ADHD? Too low levels of dopamine in a patients brain. Ritalin is then used, to regulate these levels, as with an SSRI for Depression? As far as I know, this process makes the person with ADHD calm and focused, like we who dont have ADHD usually are. This is also why Ritalin in this case makes a healthy person speed off to a sea of hightened senses. Is this correct?
Great video. I've been on SSRIs since 2003, and they helped tremendously. I was a 13 year old who was underweight, cried before school, and got shocking grades. I noticed huge improvements within a few months. I have depression and anxiety. I'm now a 26 year old with a BSc, MSc and now getting a MEng.
With all due respect, this would have been a great video 40 years ago but no professionals actually believe depression is a simple "chemical imbalance" problem any more. In fact there's no compelling evidence depressed people have abnormally low levels of serotonin or any other neurotransmitter.
Except that is not that simple. Serotonin reuptake inhibition happens in a matter of hours. However antidepressants effect does not kick in before weeks or even months. So there's something more convoluted happening and science still does not know what happens. There are different theories such as the anti-inflammatory effect of A/Ds, increased BDNF, neurogenesis and one that I particularly like: the migration of signaling proteins, esp. the Gsα, out of lipid rafts where they are not very efficient to other part of the neuron surface where the protein signaling is much more effective (the cAMP dependent pathway) and promote better cell communication.
Well, hum, in a nutshell...
What is wrong with SSRI I been taking them for 2 years now and yes I have a lot less libido but why is that a problem for a man saving money by not being interested in today's woman and saving my mental state by not being rejected by modern women I am happy feels like a huge weight was lifted off many emotions people have are sadness angry anxious etc. SSRI gave me my life would not change a thing.
matt smith You are just a weak man and its good you took yourself out of the dating pool and therefore wont reproduce your weak genetics. Your mental state would be ruined by being rejected? Haha. Modern women have their own money u money hungry weirdo
Antidepressants are medications that can help relieve symptoms of depression, social anxiety disorder, anxiety disorders, seasonal affective disorder, and dysthymia, or mild chronic depression, as well as other conditions.
They aim to correct chemical imbalances of neurotransmitters in the brain that are believed to be responsible for changes in mood and behavior.
Depression Medications (Antidepressants)
These are the most commonly prescribed type of antidepressant.
Serotonin and noradrenaline reuptake inhibitors (SNRIs) are used to treat major depression, mood disorders, and possibly but less commonly attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), anxiety disorders, menopausal symptoms, fibromyalgia, and chronic neuropathic pain.
SNRIs raise levels of serotonin and norepinephrine, two neurotransmitters in the brain that play a key role in stabilizing mood.
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants. They are effective in treating depression, and they have fewer side effects than the other antidepressants.
SSRIs block the reuptake, or absorption, of serotonin in the brain. This makes it easier for the brain cells to receive and send messages, resulting in better and more stable moods.
They are called "selective" because they mainly seem to affect serotonin, and not the other neurotransmitters.