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Support us on Patreon: https://www.patreon.com/speedpharmacology Follow us on Facebook: https://www.facebook.com/SpeedPharmacology/ Get Speed Pharmacology Merch Here: https://teespring.com/stores/speed-pharmacology **************************************************************************************************** Topics covered include: mechanism of action of adrenergic antagonists, adrenergic receptors, alpha selective blockers, alpha non-selective blockers, beta selective blockers, beta non-selective blockers, first, second and third generation beta blockers. Adrenergic antagonists mentioned include: Phentolamine, Phenoxybenzamine, Prazosin, Doxazosin, Terazosin, Tamsulosin, Alfuzosin, Silodosin, Yohimbine, Propranolol, Pindolol, Nadolol, Sotalol, Timolol, Atenolol, Acebutolol, Bisoprolol, Esmolol, Metoprolol, Carvedilol, Labetalol, Nebivolol, Betaxolol.
Категория: Образование
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Текстовые комментарии (119)
Galoo Angel (2 года назад)
it was really good and benificial sir plzzz tell me how to memorize the drugs name?? as my papers are on peek i have to work hard and im confused between all ANS Drugs
jannu harshavardhan (4 месяца назад)
About side effects of these blockers
Sabith Sabith (1 год назад)
Raisa Farhath hi
INDIAN ALPHA (1 год назад)
Speed Pharmacology
Raisa 07 (1 год назад)
Speed Pharmacology it would've been great if there was a mnemonic for the alpha blockers too sir 😐
اغاني بث (1 год назад)
+Speed Pharmacology amazing )))
A K (1 день назад)
mrkajet (3 дня назад)
What is urapidil?
Jennifer N (3 дня назад)
this is crazy good and useful! I finally understand what all these alpha and beta things are in my pharm class. Thank you so so much!! Your video is simple, straight to the point and easy to follow and understand compared to all the other ones out there.
Shene Kamal (20 дней назад)
Crystal clear ,,thank uuu♥️🙏🏻
Govind India (1 месяц назад)
best video easy understand
Cool and CRAZY (1 месяц назад)
You are the best
Noobie WatcherZ (1 месяц назад)
Edit Dec 24, 2018 .. Edit these later. 1:25 Phentolamine, phenoxybenzamine for hypertension caused by Pheochromocytoma (tumor that secretes norepinephrine, epinephrine. Acts on A2 receptors to inhibit its own release so blockade of these receptors result in more no-rep release. Norep stimulates --> B1 receptors on heart ... that's why non-select P,P can cause Tachycardia and cardiac arrhythmia. Phenoxybenzamine is an irreversible antagonist and only way body can overcome it is if body makes new adrenergic receptors which takes about 24 h. Phentolamine is reversible antagonist (lasts 4h 2:50 Selective block A1 receptors located mainly in vascular smooth muscle which reduces peripheral resistance and leads to decreased BP and also relaxes smooth muscles in the bladder neck --> USED for BPH (enlarged Prostate) 3:28 Think "zoesin" 3:40 Prazosin PDT Doxazosin hypertentsioin ( little effect on BPH Terrazosin Tamsulosin Alfuzosin BPH (little effect on BP) because these targets A1 in prostate Silodosin 4:30 Vasodilation 5:18 A & B are both has selective and non-selective 5:30 Beta blockers are competitive inhibitors at beta adrenergic receptors and they counter effects of catecholamines (Epinephrine, Nor Ep) ( which is why this is useful in treatment of hypertension, HF, H attack, angina, cardiac arrhthmias, also treatment of glaucoma and migraine prophylaxis 6:20 1st gen PIC. Propranolol, Pindolol, Nadolol, Sotalol, Timolol. acts on B1 receptors on heart --> HR down , delayed conduction through AV node and Contractility down so the final outcome is less Cardiac otuput and decreased oxygen demand on the heart muscle 6:49 Propranolol can penetrate to CNS ,, can be used for migraine prophylaxis 7:00 Timolol eye = reduces intraocular pressure 7:17 B2 receptors in lungs (*these being blocked --> bronnchoconstriction (DON'T if COPD, asthma 7:38 B blocker 2nd generation (targets B1 receptors) / cardioselective beta blockers BEAMS atenolol , acebutolol , Bisoprolol , Esmolol , Metoprolol 8:20 3rd generation has selective and nonselective B blockers. Unlike gen 1 or 2 , these 3rd generation= act on blood vessels . Non selective (B + A1 ) Carvedilol, Labetalol . B1 selective = nebivolol vasodilation by releasising Nitric Oxide from endotehelial cells. Betaxolol v .. by additionally blocking Calcium channels ( CCB) .. also can be applied to eye ,glaucoma, . 9:50 Carvedilol and nebivolol have natioxidant properties (preferred for HF also alongside commonly prescribed with Bisoprolol and Metoprolol 10:07 Intrinsic sympathomimetic properties (Pindolol, Acebutolol . Pindolol and Acebutolol not only block but also to weakly stimulate both Beta 1+2 receptors which leads to diminished effect on cardiac rate and output. These 2 are for pt who can't tolerate other Beta blockers because of pre existing bradycardia or heart block .
Ali Raza Bajeer (1 месяц назад)
Thanks for sharing brother
Prathana Tale (2 месяца назад)
Mya Xiong (2 месяца назад)
Omg... I wish I have found you earlier...
xnobodyx99 (2 месяца назад)
is panadol a beta blocker?
Clarissa Ashlyn (2 месяца назад)
I so appreciate you making these videos. Helps me study for my HESI exam!
Nata M (2 месяца назад)
ahmed meshko (3 месяца назад)
khalid abokor (3 месяца назад)
You mostly prepared it from Lippincot isn't?
sidrah tul muntiha (3 месяца назад)
Best vedio so far 👍
Ain Farhanna (4 месяца назад)
Thank u sooo sooo much
Omar Shariff (4 месяца назад)
Hi, everybody! Hello Dr. Nik
citruscyanide (4 месяца назад)
This is amazing. Thank you!
Paul H. Kircher III (4 месяца назад)
I thought having Monkey Hair meant you could turn Ween into Weezer.
Z M (5 месяцев назад)
I think those who disliked your videos are your ex girlfriends 😂 Otherwise ppl shouldn’t dislike these excellent videos lol
Rosa poya mehr (22 дня назад)
Z M I think YouTube dislike it itself lol 😆 😆😆😆
hero 2008 (6 месяцев назад)
I had ed due to over use of pains enlargement device as pump. I had symptoms called in Internet hard flaccid. Which my cc contract. I go many doctors who help nothing they said psychological ed. I read hard flaccid hf is sns reaction which made my penile smooth muscle did not relax to full capacity. Can alpha blocker help me? Because I had this chronic problem for 8 years Please help me doctor....
adil hanin (6 месяцев назад)
The best explanation ever.
Dania Sh (7 месяцев назад)
I really appreciated your videos and waiting for more, thank you a lot.
Richie Rich (7 месяцев назад)
Sakshi Bisht (8 месяцев назад)
Please make videos on CNS pharmacology, it will be really helpful ❤️
Shreekant Ujjainkar (8 месяцев назад)
FARIHA RIZVI (8 месяцев назад)
U r a gem ,thank you
Eranga Samarasekara (8 месяцев назад)
Thank you
Rathna Kumari (9 месяцев назад)
Tysm fr the video...... It is very useful n easy to learn as well........ After watching this video once if v go through the text book it becomes easy to understand... Tysm 😍
Ahmad Althabteh (11 месяцев назад)
Guys, here is a way to remember which drugs belong to what group between the 1st generation and 2nd generation drugs of the BETA Blockers. (Note: this method only works for the drugs mentioned in this video). So just remember the letter M, which is the letter that comes in the middle of the alphabet (there are 26 letters in the alphabet, it is the 13th letter). So any drug that starts with any letter from A through M (so any drug that begins with a letter in the first half of the alphabet) belongs in B1 selective antagonists and any letter that starts from N through Z (so any letter that starts with a letter in the second half of the alphabet) belongs in non-selective (1st generation) BETA blockers. Hope this helps...
Alem Hamdard (11 месяцев назад)
Tnx trillion time for ur lectures! Plzz sir cover others drugs too, and keep it Up✌✌✌
Alem Hamdard (11 месяцев назад)
Very good and fruitful short lecture! If we read the Lippincott Pharmacology book along with these lectures, it will be very high efficient for us.
Robyn (11 месяцев назад)
Wow thanks for this video, good summary with pictures!! Had to subscribe, I needed this since I have an exam and this puts it all together. Thanks again.
Dayana Wiggins (11 месяцев назад)
I really want to thank you. You have rescue my brain and I can now understand the pharmacodynamics of the ANS drugs :)
Taidus Final (1 год назад)
thanks dude your the best
viral tube (1 год назад)
Helo... You said alpha blockers used to dilates... Well all I know that this is not true... Beta blockers are responsible for dilation
Mustapha Aidid (1 год назад)
So informative and beneficial
Crystal RM (1 год назад)
Ashley. (1 год назад)
Still don’t understand ugh. Might as well quit school.
chinmayi chitale (1 год назад)
This is really helpful. Thanks a lot Sir. Helps me keep up in Pharmacology even at the last moment.
Amira Ghazi (1 год назад)
For the first time l have subscribe a channel on YouTube! your channel is really useful. I want to ask you, if i want to study pharmacology from a textbook, can you suggest one for me? Thank you.
Telesia Gerstle (1 год назад)
I already subscribe coz I’m in my mid to late 60s w HBP for the past 15 plus yrs, it’s so easy to understand & learn what alpha & beta blockers are & how they function in treating HBP & for those w heart prob, something doctors don’t do or explain b4 they write a prescription, how can a patient know & understand what & how this med that was just prescribe, I guess all we have to do is get & take, which is & have been the norm unless we ask questions, so these videos are so informative & teach us what they’re suppose to do, ThankU so much for ur kindness & good hearted work the time & effort, may God bless you & yours, w good health & happiness, especially in 2018 & beyond, keep up the good work, ThankU & Happy 2018!!
Halla Hachemi (9 месяцев назад)
it is not as easy to explain in few minutes during your visit/checkup. it is even hard for us student to understand so imagine a patient who doesnt know many of this stuff that were explained in 3 videos if almost 10min each. i appreciate your curiosity in learning how things works, but i dont think many people are willing to do the same
hiba semlali (1 год назад)
thank you so muchhhh !!!!! :))))) keep going
Perviz Ismailov (1 год назад)
How propranolol can exarcebate prinzmetal angina?
sarwan dlani (1 год назад)
Thank you so much very very useful keep going
Shivang Desai (1 год назад)
awesome man!!!! I just love all your videos
cybersphere (1 год назад)
Not a medical student. This video goes way over the head of laypeople.
Ujasa Zalavadiya (1 год назад)
plz make a more videos...it's very helpful
ROX LEP (1 год назад)
just subscribed! :)
Meg Chambers (1 год назад)
THANK YOU!!! I loved this video, its simple, clear to understand and I love the graphics that go with it. Will be watching your other videos. :)
Nathan McKaskle (1 год назад)
I wonder if selective beta 2 blockers would be good for essential tremor.
Marko Petrović (1 год назад)
As I recall, they are used for essential tremor as well.
Heikkie Nehale (1 год назад)
Thanks a lot...this is amazing explanations.
Mahnoor Azam (1 год назад)
Shorouk Salem (1 год назад)
Really useful channel thank you , we hope you do more videos i wish i could have these videos during my medical school time
Cowtippin23 (1 год назад)
Thank you thank you thank you! I have a patho/pharmacotherapy test next week and I learned more from you than my teacher!
Sumit Gupta (1 год назад)
thank you sir...👍👍
111mmgg (1 год назад)
You my friend are one SEXY HUMAN BEING 😘
bana daboul (1 год назад)
I have been reading for two hours about alpha blockers but there were many things I didn't understand. In here only five minutes but It did answer all my questions. Amazing ,Thanks 😄
jim dee (1 год назад)
2017 and people still use chemical crap while they could try magnesium first, without all the side effects
funkyflights (1 год назад)
gil bkk .... Sometimes you need chemical crap, not everyone's blood pressure is controlled naturally... The silent killer takes lives all the time when blood pressure is not controlled... Also heart rhythm disturbances can kill people without these drugs ...
Saqi Rashiq (1 год назад)
Great job..Want more elaborate discussion
Angelina Jhonsan (1 год назад)
Dude Where Were You my whole LIFE when I Was Being Tortured By Pharma.......😍😍😍
No this is Patrick (1 год назад)
Great videos!
Dien M (1 год назад)
i'm just gonna say that you're Wonderful!!! thank you!! (and very smart too) <3
Drew Stalinsky (1 год назад)
Great explanation. Helped me in my pharma class. Appreciate the sharing and simplification of information.
kaou bou (1 год назад)
waaaoooh ! waaooooh ! thank you ! it's genious ...we need your vidéos and we hope that it will be in french ! pleeeeeeaaase I'm in love with your vidéos ! so please ... make them with french for the sake of God
Primrose Madzinga (1 год назад)
you are good
Primrose Madzinga (1 год назад)
you are good
Ghassani Izlyn (1 год назад)
I want to ask something: 1.In previous video norephineprin mainly stimulate alpha 1 receptor which increase blood pressure and almost dont stimulate beta receptor. But here, norephineprin stimulate beta 1 receptor and not alpha 1 receptor? 2. In nonselective alpha blocker, alpha 1 & alpha 2 blocked. Alpha 2 blocker causes norephineprin release more, but why it doesnt have an effect to alpha 1 receptor that cause increase blood pressure. And moreover nonselective alpha blocker used for hipertention that needs low blood pressure. I still get confused abt this, please answer me, thank you..
Ghassani Izlyn (1 год назад)
Ow i thought its only have alpha 1 effect.. Thanks a lot 😊😊😊
Kazmer (1 год назад)
1. norephineprin stimulates alpha 1 as well as beta receptor but it has increased affinity to alpha 1, this does not mean that stimulates only alpha 1, it means stimulates alpha 1 more than the beta. 2.Alpha 2 blocker does not have direct effect on alpha 1 receptor, but due to norephineprin release it increases blood pressure beacause the beta 1 effects are taking place (reflex tachicardia). i hope it helps you, have a nice day!
Maira Khan (1 год назад)
best lectr....very easy to understand.
Nousheen Rashid (1 год назад)
very very good, it's very precise and very accurate, like your way teaching.
MIATTA NYANA BRIMA (1 год назад)
Tnx loadz.👍
MIATTA NYANA BRIMA (1 год назад)
Tnx loadz.👍
MIATTA NYANA BRIMA (1 год назад)
Tnx loadz.👍
Fatima Cheema (1 год назад)
Umm Clonidine and Methydopa are alpha 2 blockers used to treat ADHD and Hypertension...You may want to update that.
Urav Patel (1 год назад)
FAYYAZ HILALZAI (1 год назад)
Fatima Cheema alfa 2 agonists not blockers
salaams14 (1 год назад)
Your videos are great! very clear explanations, good speaking tone, and easy-to-follow flow charts! Thank you
Sara Alariki (1 год назад)
wonderful explanation. i hope u make antibiotics videos
Lynne Cota (1 год назад)
This was a great video. Subscribed to your channel. I appreciate the time you put into making it. Thank you!
Kül Tégin (1 год назад)
Hey i would like to translate and release video with Turkish subtitles.Can you allow me?
Mr. Musician. (8 месяцев назад)
Dose that permission include reuploading the video on his channel!?
Speed Pharmacology (1 год назад)
Yes. Feel free to translate any of my videos. Thank you
Rudyrose3 (1 год назад)
G M R (2 года назад)
awesome video but fix the damn mic
Sumaira Naz (2 года назад)
thank you so very much. Now I can see why I have different response to carvidilol and nebivolol
With Love, Michelle (2 года назад)
These videos are awesome and very helpful. Please upload more
Ahthesham Sheikh (2 года назад)
Excellent video, very sharp presentation. Thank you. Go on 👍
Shrankhla Paliwal (2 года назад)
loved these videos of urs on ans...thnx so much!!
dinobutt1988 (2 года назад)
Thanks for this channel. I'm currently working on my pre-reqs to apply to pharmacy school. However, I wan't to try to learn as much pharmacology as I can to truly be prepared when I get accepted. Keep the videos coming, you have a new subscriber.
كياني ملكي (2 года назад)
Thank you so much tomorrow I have finally exams and you helped me 🙁❤️❤️
Zain Alabedien (2 года назад)
your videos are the BEST
Arpan Pramanik (2 года назад)
thank you speed pharmacology very much
fabithom (2 года назад)
what about mirtazapine as a selective a2 receptor blocker?
Paper Works (2 года назад)
whoa! I can understand this. My professor seems to be talking in another language when discussing these but you've made it simple and easy to understand. Thank you very much and keep making great videos!
Sakshi Garg (2 года назад)
thank u sir....😁
nab el (2 года назад)
great video, but I thought norepinephrine is secreted by sympathetic neurons, not adrenal medulla. thx
jacqueline michael (2 года назад)
very clear explanations, thanks a lot for your videos.
M.k_ Ali (2 года назад)
Thank you for your helpful videos and tips.
Hassan Naseer (2 года назад)
please upload cvs topic
Ahmed ali (2 года назад)
for the first time in my life I finished a Pharma topic without falling asleep :) thank u so much and keep going
Zach McCallips (2 года назад)
Just discovered this channel while studying for my pharmacology exam tomorrow, and I saw this video was uploaded just yesterday! Thanks for coming in clutch, and keep up the great content!
Nada Sawyer (2 года назад)
good ,, keep goin

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