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The basal ganglia - The direct pathway | Nervous system diseases | NCLEX-RN | Khan Academy

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Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT related content. These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Khan Academy video. Created by Emma Giles. Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/rn-nervous-system-diseases/rn-parkinsons-disease/v/the-basal-ganglia-concepts-of-the-indirect-pathway?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn Missed the previous lesson? https://www.khanacademy.org/test-prep/nclex-rn/rn-nervous-system-diseases/rn-parkinsons-disease/v/non-movement-symptoms-of-parkinsons-disease?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn NCLEX-RN on Khan Academy: A collection of questions from content covered on the NCLEX-RN. These questions are available under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States License (available at http://creativecommons.org/licenses/by-nc-sa/3.0/us/). About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s NCLEX-RN channel: https://www.youtube.com/channel/UCDx5cTeADCvKWgF9x_Qjz3g?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
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Текстовые комментарии (46)
Kasem Sawaed (9 дней назад)
Is it that easy? Lol.
Fathy Mohamed (1 месяц назад)
you made it easy, thank you
Ann Behanan (2 месяца назад)
this is amazing!
krupa danam (2 месяца назад)
thank you very much
Vaishnavi Karpe (2 месяца назад)
Wow you made it so simple to understand!! Thank-you!!😊
Lenovo Legion Y520 (3 месяца назад)
thankss ! soo helpful
Ayesha Bibi (4 месяца назад)
Teacher! you are a blessing
Abd Ur Rahman (6 месяцев назад)
You're voice is so clear and nice way of teaching you got
Dr. Mohamed Fayez (7 месяцев назад)
Remember Basal ganglia by 5 S https://youtu.be/hcsAnQXzGPI
der highfish (7 месяцев назад)
it's said the striatum sends inhibitory signals to the globus pallidus but the globus pallidus is a part of the striatum, should be a little more specific there
aprilneha (5 месяцев назад)
globus pallidus is not part of the striatum. the striatum is the putamen and caudate
Vinesh Manohar (7 месяцев назад)
Thank you. Really helpful :)
dharani sudha (8 месяцев назад)
Clear and simple..tnq😊
ಗೋಕುಲ್ ರೆಡ್ಡಿ (8 месяцев назад)
Amazing ....I got the concept😍
BDaKing94 (9 месяцев назад)
took my professor 90 mins to explain this, and i was still confused came here watched once it now it all makes sense Eureka forrrealll
margo1993 (10 месяцев назад)
Great, simple, very informative. Only one question: what stimulates Subthalamic Nucleus to send an excitatory signal to Substantia Nigra?)
Shouq Mohamed (11 месяцев назад)
this was faaaaaantastic
Triana Hardianti (11 месяцев назад)
thank you so much for this concise explanation! but could you please tell me, who order the subthalamic nuclei to excite at the 1st place? thanks!
vinestreet7 (1 год назад)
Love your voice. So pleasant to listen to. Thank you.
Miz Rahman (1 год назад)
thank you so much, this explanation was so clear. I wish she was my neuroscience lecturer loool
Ricky Storrie (1 год назад)
what about dopamine?
Ahmed Gharawi (1 год назад)
I love u ;)
eliska mataskova (1 год назад)
why can't lecturers at uni be like this pls? they made it sound so complicated and it is actually pretty straight forward. thank you <3
Khamis Zananiri (1 год назад)
the best presentation i have ever seen concerning the basal ganglia. congratulations and thanks. YOU ARE THE BEST
Nouf Saud (1 год назад)
I’m wondering how all khanacademy members have flawless handwriting!!
Noxolo Luthuli (1 год назад)
wow thank you
aswini ms (1 год назад)
wow super
DR SULTAN SAUDAGAR (1 год назад)
awesome video
quite zone (1 год назад)
great explanation
Could you please tell me what is the program used in this clip? I have to make a clip for my senior project. Any recommended programs ? Thank you:)
Bahdon Cali (2 года назад)
thank you very much :)
Xavier Ang (2 года назад)
In this video you state that the "Thalamus" is always in inhibition. However, in your indirect pathways and your PD video. You state that the thalamus is always excited like a dog. So which is it? always in inhibition or excitation?
Matthew Enriquez (1 год назад)
The thalamus is always excited like a dog by default. The globus pallidus is always keeping it inhibited tho, like an owner controlling his/her dog. That's what I got out of this, anyway.
bilbo (2 года назад)
Hello, In a resting person, the THALAMUS is under constant inhibition from the GLOBUS PALLIDUS. (To prevent it from sending a signal to the cortex thus avoiding making an unnecessary movement). When one wants to make a movement however, this inhibition is cut off. additional: the thalamus does not need an activation signal. All it needs is for the inhibition signal to be cut off, his is because, it is always ready to fire if not inhibited. (thus is why she said it is always active) I hope this helps. good luck with your studies.
Channi Roth (2 года назад)
Great video
Tim De Boeck (2 года назад)
Awesome video!
Michael Darby and Smile (2 года назад)
What is the name of the excitatory neurotransmitter that goes from the subthalamic nucleus to the substantia nigra?  Is it Glu or Dop or something different? Also coming back is it gaba?  It would be very helpful if you included all neurotransmitters in the future. : ) LOVE your work!  I don't know if you work in connectomics much regarding the 3 types of learning in real time....(physical structure of content, history of content and real time experience of content) I think your mother type voice regulates students making it easy to learn...lol....I know it sounds crazy but I think there is some truth to this.  I found it much easier to learn from your videos....I believe I already have circuits in place that recognize the soft tone of your voice....from -9 months to 8 years old my mom had a very gentle tone as I imagine most moms do.  Anyway, the point is when we are regulated it is much easier to learn. : )
Christoph Eidherr (3 года назад)
very well and evenly understandable explained. thank you! :)
Lucas Prust (3 года назад)
I thought that striatum inhibits globus pallidus (ext), that inhibits globus pallidus (int), therefore the striatum activate the global pallidus (int). Can someone explain this to me? I'm very confused now.
Neil Parikh (3 года назад)
+Lucas Prust Sorry if this is too late, but you appear to have slightly mixed up the indirect and direct pathways of the basal ganglia. The direct pathway was outlined correctly in the video; the indirect pathway DOES involve the striatum inhibiting GPe, but GPe inhibits the subthalamic nucleus (NOT GPi) which normally activates GPi indirect inhibition of GPi). This consecutive inhibition acts as an activator, and upregulates GPi inhibition of the thalamus. The overall effect of this pathway is inhibition of movement. However, D2 (dopamine 2) input to the striatum actually inhibits this pathway, leading to decreased inhibition of the thalamus (usually translating to increased movement).
jcash (3 года назад)
why isn't sal doing these
David Ndiulor (3 года назад)
Wow, I love medicine.
Eddy Allenby (3 года назад)
You just blowed up my brains!
DEVIL*# chaser (6 месяцев назад)
Eddy Allenby r u alive then
Joanne Chan (3 года назад)
Learned this in neuroanatomy this week so great timing to revise :-)
Bibek Timilsina (3 года назад)
10 mins gone in a blink, so good and simple; thank you!!!!!

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