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Pharmacology - PHARMACOKINETICS (MADE EASY)

Оценок: 3728 | Просмотров: 322105
Support us on Patreon: https://www.patreon.com/speedpharmacology Follow us on Facebook: https://www.facebook.com/SpeedPharmacology/ Get Speed Pharmacology Merch Here: https://teespring.com/stores/speed-pharmacology **************************************************************************************************** Topics covered include: absorption (passive diffusion, facilitated diffusion, active transport, endocytosis), distribution (volume), metabolism (phase I, phase II), elimination (zero, first-order kinetics), steady state, cytochrome P450 (inducers, inhibitors)
Категория: Образование
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Текстовые комментарии (125)
Brodie Gies-MacNeil (4 дня назад)
Amazing! More informational and clear than my actual lecture.
Random Girl (8 дней назад)
Thank u sir..good way of teaching..
Thomas Lau (13 дней назад)
Like this lecture. It helps.
Jacky (13 дней назад)
Amazing video. Very informative. I was wondering if you could make a video with a stepwise tutorial of the phase 1 and phase 2 mechanisms of elimination. My professor’s explanation is a little wonky. Thanks 👍🏻👍🏻👍🏻👍🏻👍🏻
فورت نايت 12 (14 дней назад)
Awesome 👏🏽
sai pharma (1 месяц назад)
thanks for making this videos
Chirag Boghani (1 месяц назад)
Very easily explained with fun too
herdior (1 месяц назад)
@11:52 it should be R=O at the oxidation, right? Great videos anyways!
Susovan Halder (1 месяц назад)
These are gems sir! Awesome videos! Can you please upload something regarding neurotransmitters and antiepileptic drugs?
Saeed Anwar (1 месяц назад)
You are just awesome plz upload more videos on other topics as well we neeeeeed ur help maaaannnn
Missqueenxie (3 месяца назад)
This is so helpful to study my Biopharamaceutics. Your videos are so helpful to me as a Pharmacy student 😭😭😭 thank you. Its so easy to understand
Hussein Farag (3 месяца назад)
Such an informative and simple way to illustrate the complex concepts of pharmacokinetics, thanks man.
Rachel Petrillo (3 месяца назад)
His accent reminds me of Doctor Doofenshmirtz from Phineas and Ferb! (This is not an insult, you're an amazing instructor thank you).
Sandhya Dhital (4 месяца назад)
Thank you so much! This was a great video! very helpful!
Bella S Oktora (5 месяцев назад)
Thank you! I love your channel! New subscriber 😊 please keep making Pharmacology video ❤
SuperZan (6 месяцев назад)
appreciate it bro, it was really good summarised most of the essential stuff i needed to revise
Sahar abdul karim (6 месяцев назад)
where is metabolism?
xMyShatteredDreams (6 месяцев назад)
You forgot to mention absorption through bulk flow, filtration, exocytosis, ..
Coral crue (6 месяцев назад)
more videos please
Ha Neul (7 месяцев назад)
Good job 👌🏻 . Thank you 😊😊
Still Mylarh (7 месяцев назад)
Amazing 🙏🏽
Laveesha Kumari (8 месяцев назад)
Thnkxxx....alot sir It laid me to sit ...for pharma ...😊
Umair Bhurgri (8 месяцев назад)
You're amazing!
Maha Yousaf (8 месяцев назад)
plz make more vids like this you saved my pprs
PsYcHo-PuNk (8 месяцев назад)
thank you this was very helpful
Imran Kahn (8 месяцев назад)
Excellent video I like it.
Charles Darwin (9 месяцев назад)
damn, i fell asleep
Hudaabdlh (10 месяцев назад)
Great video, helped me kick-start a difficult module this coming trimester :)
Norfa Hadjilatip (10 месяцев назад)
Hi. I'm just gonna ask a permission. Can I use this for my report? Thank u :)
Crit-IC (10 месяцев назад)
Nice video sir! Keep it up!
Yashashree P (10 месяцев назад)
I coudn’t concentarte what u were saying I was looking how u were drawing ur diagrams😂🤣
yousof khan (10 месяцев назад)
Its helpful,thnks
alina ali (11 месяцев назад)
awesome and it really speed up me in pharmacology short but brief explanation....thank you
mandip haran (11 месяцев назад)
100 claps thousand thank you to u sir # thank you so much for helping me
Afreen Qadir (11 месяцев назад)
wow...wow...wow...all the lectures of speed pharmacology are just super awesome...I start enjoying pharma..thanku so much sir
Fatma Salman (11 месяцев назад)
thank you , great help
Toon Holman (11 месяцев назад)
Wait. Isn't half life useless in 0-order kinetics?
Ansuk Shukla (10 месяцев назад)
Toon Holman yeah, the half life for zero order kinetics is dependent on the plasma concentration at that time. It is not constant.
Mazen Elsawaf (1 год назад)
Thank you sooooo much....You are simply pretty clever...god bless you ❤❤
Awesome video...thank you sir
deathstroke 21118 (1 год назад)
Thank you <3
Abdul Ghafar Noonari (1 год назад)
Thnku so much..
jack950123 (1 год назад)
why my nursing school taught me: zero order drug half life = Initial Conc./2K First order drug half life= 0.693/K that means zero order drug elimination depends on the dose while first order drug is constantly eliminating This is opposite to yours! WHY?!!! I am so confused.
nikhil twister (1 год назад)
awesome video, but isn't the half life is mainly based on 1st order kinetics?
Maruful Bhuiyan (1 год назад)
Thank you!!
FacelessMan6212 (1 год назад)
Outstanding. Thank you!
Julia W (1 год назад)
very helpful thank you :) PCRABS made me laugh!! but I will remember it because of that!
nicholous bhusal (1 год назад)
really grt,, m doing pg preparation n it provides perfect concept,, thank u n hope 2 c more,,,
Miguel Ángel Siller Uvalle (1 год назад)
Wonderful stuff
Anas yousif (1 год назад)
What is the difference between the pharmacogenetics and pharmacokinetics and pharmacodynamics
Pharmacognosy (1 год назад)
Anas Yousif Pharmacogenetics is the effects of the genetic factors on the reaction of the drug, Pharmacokinetics is what the Body does to the drug (ADME or LADME) and Pharmacodynamics is what the drug does to the body.
nazirahidris (1 год назад)
great job!
CSUSM 102 (1 год назад)
Great concise vid!
mrs.a (1 год назад)
you sound like danas bf (wanted adventure) 😅
Abhishek Arora (1 год назад)
please add metabolism sir i think u frgot
WATCH ME (1 год назад)
Perfect!!!!
Sareen.A.Kadkade (1 год назад)
Wow!! This is fascinating. Thanks a lot for the upload.
mohammad shahid (1 год назад)
you are good but just speed up a bit & make a lil shorter vedeos convenient for us u know 😊
Ahmed Elzoghbi (1 год назад)
يطعمك ما يحرمك يابني بقالي عشر سنين بحاول افهمها مش عارف :) :) :)
argumentumadbaculum (29 дней назад)
You are an excellent teacher
Shosho tv (9 месяцев назад)
😝😝😝😝😝😝😝😝
Beedy KH (9 месяцев назад)
يا ساتر عشر سنين! انا اخذتها محاضرة وحدة وفهمتها. بس داخل اقيم المقطع واعدله لو في اخطاء بشرحه ;)
Shosho tv (11 месяцев назад)
Ahmed Elzoghbi 😂😂😂😂 نزلت التعليقات بشوف في عرب ولا لا.. الحمد لله لقيتكم دلوئتي مش حاسة بغربة 😂
lina 94dhyaa (1 год назад)
اي والله صار سنين مفاهمتها
Ayomide Akin (1 год назад)
great video! where is this accent from?
greimalkin (1 год назад)
if a protease inhibitor inhibits cytochrome p450, does that mean that protease ( like taking a digestive enzyme) would help make the enzymes work?
greimalkin (1 год назад)
8:16 elimination
Harshitha Ramesh (1 год назад)
Thanks. that was simple and easy to understand😃
jnxmaster (1 год назад)
Awesome video! Love your voice :D Thank you.
Sadiq Urrahman (1 год назад)
Welldone sir
Kam Lesh (1 год назад)
thanks a lot brother you done a very outstanding job
Chirodeep Basu (1 год назад)
Truly kept easy and simple :D Thanks for making such videos!
chiko9100 (1 год назад)
isnt transport through channels also considered facilitated diffusion?
Speed Pharmacology (1 год назад)
yes, as long as it's not energy dependent
Pride Comeon (1 год назад)
Plz make videos on macrolides
pramodya bandara (1 год назад)
thank you so much. this was so helpful. can you plz do more videos?
Priscila Santos (1 год назад)
Thank you! Thank you! Thank you! More pharmacology videos, please.
abhilash devarapalli (1 год назад)
Those videos are just awesome
abhilash devarapalli (1 год назад)
But more videos from Rx will be soo good 👍🏻
JoannaBanana415650 (1 год назад)
I'm loving your videos dude. Keep it up!
Norah Salman (1 год назад)
this is very helpful thank you
maria nuh (1 год назад)
Thank u alot u make it easy
Amani Miskey (2 года назад)
Great video !! but I didn't understand the first and zero order kineticts
Eccentric M.D. (2 года назад)
You just save my life in med school...Thank you for making such a wonderful video....I can now take on Pharmacology
amina ashrafi (2 года назад)
thank u so much for the video sir! it's really helpfull... :-)
Richie Venegas (2 года назад)
What type of Mathematics would be more beneficial to Pharmacology , Statistics or Calculus?
Habill Zain (2 года назад)
thanks..
Manjinder Pabla (2 года назад)
great..thank you !!! keep going !! :)
Mallika B (2 года назад)
Fabulous video.....helped me a lot .Thanks :)
shanella charles (2 года назад)
The best video I've seen so far .
malgorzata kita (2 года назад)
professor Fink is master of explanation,but this one as very quick reminder is fine.
Amira Lam. (2 года назад)
you just saved my semester, thank you a lot!
Sam Washington (4 месяца назад)
you passed the exam?
Shayma Alb (2 года назад)
great video👏 loved the explanation
Lauren Harrison (2 года назад)
This video and your pharmacodynamics video have helped me cram for the Pharmacology component of my medical exams :'D Thanks so much!
Ben Aguilar (2 года назад)
Did not expect Jar Jar Binks to be so good at explaining Pharmacology Just messin w ya ma great vid
John Tuffield (16 дней назад)
I should not have read this comment before listening to the video. Now Jar Jar Binks is teaching me about pharmacology.
aqsaa mohammed (24 дня назад)
Ben Aguilar m
Hasthi Gunaratne (4 месяца назад)
lmao
Severus Snape (10 месяцев назад)
Darth jar jar
Ruben Wahab (1 год назад)
Couldn't unhear that lol great vid!
Scirvir24 (2 года назад)
For real, these videos are beyond helpful. Keep up the good work, man.
Simon (2 года назад)
i love the videos.... place keep on making more!!!!!
Musheer Khan (2 года назад)
add more videos...
Mark Robertson (2 года назад)
Excellent, thankyou
moben kane (2 года назад)
excellent,,,,, great job , ,,,
brahfaanicus (2 года назад)
These are awesome - I really hope you make more!
zishan ahmad (2 года назад)
nice
Snow Shine (2 года назад)
thanks a lot!!! this helped me understand clearly :)
Snow Shine (2 года назад)
thanks a lot!!! this helped me understand clearly :)
Nicole B (3 года назад)
Very helpful, thank you!
majesticalps (3 года назад)
you're an absolute legend. thank you so much!!!!!!!
radja deghmine (3 года назад)
thank you ,,, very helpful
an33za (3 года назад)
Just wondering how does our body follows mathematics (in reference to first and zero order kinetics)? I mean fixed fraction or fixed amount getting eliminated over a (fixed?) Period of time is something so not random as i first expected... Grabbing these concepts first yourself and then finding a way to explain in tutorial form to us must be so time consuming and hard work by you. Very impressive! (How do one present the topics in as much innovative way as you do?)
Lorenzo Carnio (5 месяцев назад)
Think about it like this, you have two workers, one of them can remove 5 cups per minute so no matter how many cups you stack in front of him, the maximum cleared amount in a minute (or whatever unit of time you choose) is 5 cups. The fraction changes because its dependent on the denominator (how many cups are left). 5 cups out of 100 gives you a 5% clearance, while 5 cups out of 5 gives you 100% clearance. The longer the 5 cups per minute is allowed to work without adding new cups, the "more he cleans fractionally" but its always the same number of cups. On the other hand, your second table has a machine that can only remove exactly 1/4 of the total amount of cups per minute (or unit time). Now we can see that instead of changing the number of cups by a static amount (5 cups) we are changing it based on how many cups are left! As a result, starting with 100 cups, removing a quarter puts us at 75 cups, but the next time the machine removes a quarter its going to drop the 75 by another 1/4! It doesnt care how many cups it removed, only how many are left. hope this cleared it up
nicola tumedei (1 год назад)
I guess, it's because usually in zero-order kinetics, the drug saturates all your enzymatic systems for excretion/biotransformation, etc... so the rate of elimination is not dependent on the drug concentration and it's fixed over time, so graphically it's a straight descending line. On the other hand, in first-order kinetics your systems are not saturated and the rate of their reactions is dependent on concentration (see Michaelis-Menten equation).
Angelxbaby88 (1 год назад)
i still don't understand why the fraction is different in zero order though
monkiram (2 года назад)
+an33za It's not really that your body follows mathematics, we come up with mathematical laws to predict and understand the body. In first order kinetics, the more of the drug you have, the more receptors work to degrade it, and usually that fixed percentage of the drug cleared reflects how quickly the receptors can degrade the drug. In zero order kinetics, the receptors have become saturated, so they're doing the maximum amount of work they can do. That means, if you take more drug, you don't have more receptors to breakdown the extra amount of drug, the receptors are already breaking down the maximum amount of drug per unit time, so it's going to be a set amount of drug. These are properties of how the body interacts with the drug, and scientists have observed this and graphed it in order to try to get a better understanding of it. I hope that clarifies a bit
Speed Pharmacology (3 года назад)
+an33za keep in mind that this is not an exact science. however mathematical models can provide useful insight into pharmacokinetic behavior of a drug despite their much simplified depiction of human physiology. good question
an33za (3 года назад)
Drawings so amazing making these concepts a lot of fun to remember, and accent is cool n distinctive too with much command over the subject :) Thanks!! (Btw just curious to know which tablet or software u use for these videos)
happygirl308 (3 года назад)
wow this is awesome thanks!

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