Depression is a complicated illness and the main form of treatment comes from antidepressants, but how do they work?
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What causes depression?
“It’s often said that depression results from a chemical imbalance, but that figure of speech doesn’t capture how complex the disease is. Research suggests that depression doesn’t spring from simply having too much or too little of certain brain chemicals.”
How Anti-Depressants Create New Brain Cells
“Antidepressants increase the presence of a growth factor in the brain, which then leads to a proliferation of new cells, according to a study by Yale School of Medicine researchers.”
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I don't think there is such a thing as chemical imbalance. Chemical imbalance would suggest our minds are just chemicals and we have liitle or no control over such chemicals when it seems clear we have a soul, a unique personality. Depression is reactive based on external stimulai. I don't believe anyone is predisposed to depression. That gives depressed people an excuse to be depressed! Your childhood/teenager years are crucial in how your adult brain works. My guess is all adults with depression have had some major anxiety trigger from their earlier years.
I tried them, and PLEASE DO NOT GET THEM!
They numbed my brain which was good, but they made me think of suicide plenty of times, I even got caught with a belt around my neck. It makes you feel more suicidal.
This is some very one sided information. The larger picture is that sleep and exercise are about 7x more effective than SSRI's. SSRI's improve about 1 point on the depression scale. A effect, yes, an "incredibly effective effect" no. SSRI's have side effects, and can mess up your brains re uptake of serotonin even after stopping SSRI's.
I really want to know why I struggle to find reasons to live and as such destroy relationships and my life even though I have taken so many antidepressants and they don't work and neither does therapy?! I need help that doesn't exist yet. Video was informative though but it just makes me question more why it isn't working :'(
I’m 11 and I’ve been bullied and I’ve been depressed for a long time and people are trying to get me on them but I haven’t got them yet as people think I will help me has anyone else been on them who’s my age???
Grow up or be in a negative environment, lack vitamins, eat shitty food, drink bad water, seek assurance from a greedy doctor which will build the belief,.. is it... common sense? Nobody is born depressed, something always causes an imbalance, even being yelled at during young age, that gene (if it is even accurate) may just be the activator, and your personality type
Why the human is the only species on earth that suffers from depression,diabetes, cancer ..etc? What if the food and water that we take from supermarkets + the radio frequencies(which are a lot around us)+ the media, are the cause?? I think that somebody want to kill us slowly and makes us suffer.. And generally the dumber people is the one that never suffer from depression :c Thats why when people are on drugs or alcohol they are happier(dumber too)..
Marcelo Velarde Not exactly true as I had a dog and even a cat who suffered from depression when we introduced other animals in our household. Could be because our pets are subject to the same pollutants and procesd foods that we subject to. I think the reason some "dumber" people suffer less from certain could be because they think less then more intelligent people so less likely to dwell on negative taughts.
Taking antidepressants is probably one of the worst things you can do to yourself. Strange seeing how most school shooters were prescribed antidepressants and committed their acts within withdrawal from them. These meds should be banned but big pharma needs to make their money by manipulating the people into believing that these "happy pills" actually make us happy.
I'm back on antidepressants because I nearly tried to kill myself yesterday. For anyone who's never tried antidepressants or is going to have them I'd say that they do kind of work they don't exactly make you happy or sad they will make you feel numb to the world and they can stop suicidal thoughts and anxiety that's all they can do.
the thing with anitdepressants is, is that it often only deals with the symptoms and not the actual root of the problem. Antidepressants can be used, but therapy often works a lot better. Doctors prescribe antidepressants because there is little to no time to talk with patients: it's a simple solution, but it doens't quite cure the actual desease. Also, like mentioned in the video, antidepressants mainly work for people who have a severe depression; people who suffer from a 'lighter' form are barely affected by the pills. On top of that is the fact that young people actually have an increased chance of committing suicide when they are on antidepressants.
I'm not claiming that you shouldn't take the pills nor that you shouldn't seek help, you absolutely should if you struggle with mental illness! just be sure that you read up about what the effects of the meds are and discuss with your doctor what the best solution is for you. don't be too swift with grabbing for the pills, therapy works wonders if you open up!
I quit my St John's Wort usage cold turkey just recently. (Tried a prescribed antidepressant once and tried to commit suicide with those pills, how ironic.)
I'm interested in microdosing 1P-LSD.
I tried eating cannabis but only used strains high in THC, because I grew it myself and so it was very cheap, so it usually just got me high or stoned: not super useful for practical, daily use. Maybe I should give CBD-oil a try.
But I heard great results on psychedelics. Psychedelics are amazing in their own way anyway.
I took something similar today, I got through the day without over thinking and thinking crazy thoughts, which make me go mad. To be honest, I felt happier, I walked and noticed the trees and lights more than the people passing by. I do not know what exactly I have since I haven't seen a doctor, but all I know is that I think things that aren't real, I think of killing people I get angry over, or simply think bad things in general, which cause me to think the world and even my family is against me, even though my family loves me. If I have to take meds, which will cause my life to shorten let's say from 40 more years to 20 years, I'll gladly take it for the sake of being happy and keeping my sanity.
I took them on and off
Many of antidepressants
They never made me feel zombie nor empty like most people experienced
They just made me in a better mood and more optimistic that's all
But they didn't help with my fatigue low energy and motivation
And sleeping for long hours
Also they cause me to sweat a lot and low libido,
so they really don't work much on me, and i am trying to figure out other methods.
Ive been thinking about getting on antidepressants for a long time now, the sweat and libido thing doesn't really matter to me becaus i have no sexlife to begin with. And i bath alot, and for long.
But would you say it's worth it?
I'm 16 and I might be suffering from depression I've been like this since i was 6. I wanted to kill myself. 2 day ago I had a break down in school for 3 hours and I had to wait for my mom to pick me up so she can take me 2 the Rutgers mental health building and they said I should have an emergency health screening. I'm kind of scared to take these medications if I do come out positive for depression because I have bad anxiety and Idk how to explain it. I'm already diagnosed with ADD tho. but the worst thing about this is the fact that wanted to kill myself at 6 and now I'm 16 and about 2 be 17 in 4 months and still feel this way is the worst thing ever. I think about doing it whenever it decides to pip up in my head to technically it never goes away it just has its time when it comes. and I've tried but not to the extreme because I'm to scared. I never did self harm tho. but I feel sad all the time and I feel different forms other people and every one is so happy and so social and I'm just the odd one out with a few friends and I'm scared to talk. tbh right now I feel like crap.
Nice video content! Sorry for the intrusion, I would appreciate your thoughts. Have you thought about - Lammywalness Erase Depression Guide (do a search on google)? It is a smashing one of a kind guide for beating depression minus the normal expense. Ive heard some incredible things about it and my best friend Jordan after a lifetime of fighting got amazing results with it.
It's strange the comment section is full of people who accuse the pharma industry of falsly advertising and marekting thier products. (At the same time it seems like these people can barely spell).
I came here to find answers and left even more confused.
There are many components to treatments for depression. One plan I discovered that succeeds in merging these is the Martos Magic Method (check it out on google) it's the most useful guide that I have ever seen. Check out the awesome info .
'Antidepressants' is a brand name. The industry is colossal. Pain hurts, but serves a purpose that benefits you. These are sedatives, designed to numb you to reality, whilst taking money from you. It's like being told that somebody that only ever asks you to shut up is a good friend. Please trust that the solution always is, quite literally, working out what you truly want in this life, and then trying your hardest to pursue it. There is no failure other than never having tried. Steer clear of these drugs, you should be proud of who you are.
Depression is so varied that a psychiatrist must know all the types and subtypes of it, as well as all the effects of the various antidepressants to be able to really help a patient. My version of depression is mixed with anxiety and OCD-s, so he chose escitalopram (Lexapro for Americans). Good choice overall, and it worked in killing the pulses of negative thoughts that assaulted me throughout a day. But it also causes wakefulness surges. Bad, because I'm a fragile sleeper.
solution is not antidepressants, nor any drug, but a plant based diet and correcting vitamin d deficiency, so sun every day at least 20 minutes, and also correcting other deficiencys such as magnesium and zinc that also regulate nmda glutamate receptors and bdnf. drugs only treat symptoms and cause an unnatural hormonal imbalance in your brain and your body, check out nutritionfacts.org here on youtube or his website with that same name... (dr michael greger)
After nearly 20 years passing since first taking them I've found I recover quicker and can stay happy indefinitely by NOT taking these drugs. On them it takes much longer to get better and I lapse back into depression within 6-12 months regardless of wether I stay on them or not. To me that means they turn my depression into a chronic illness rather than treat it. Maybe they work for some people but you should be wary as I spent many years believing them to be helpful when for me they clearly weren't.
+LMNOP You'd be surprised at the recent studies tending to confirm the ¨dodo bird¨ theory of psychotherapy: that what really matters is the quality of the therapeutic alliance and the nice personnality of the psychologist and that the actual form psychotherapy takes is of little importance. In fact, much like with any other mental disorder, depression has no know official causes, and without knowing the causes of a problem it's hard to come out with a treatment that is really effective on a consistant basis. The best they can do it throw everything but the kitchen sink at the problem until something finally seems to stick a little, then run with this for a couple of decades, until something else seems to stick a little more etc. The actual research on antidepressant is gravitating towards ketamine and moving away from ssris while antipsychotic medication research is moving away from the dopaminergic model in favor of working on glutamate.
Milky Lamb That meta analysis also shows that exercise, antidepressants, psychotherapy, or combinations of them are all equally effective. So if all of these have the same effectiveness, then they must all be the active placebo effect. Yet the meta analysis does not talk about that. The meta analysis does say that antidepressants are effective, but that the risks of side effects make it less worth it than other methods. However, how can you expect a legitimately depressed person to exercise regularly when most nondepressed people still cant find motivation to exercise, or how can they all be able to afford expensive therapy sessions for years?
+LMNOP It's not one study, it's a massive meta-analysis of most published and especially unpublished data on four different antidepressants (Kirsch 2008). Psychiatrist's ¨clinical intuition¨ is not scientific. At the very least, I can tell you I have tried no less than 5 different antidepressant, and none of them did anything.
Milky Lamb They are, unfortunately most people have trouble finding the right meds. A study doesnt account for that. Any psychiatrist will tell you that they work very well, but for whatever reason one might be completely useless for one person while being amazing for another
No study has ever been able to show prescription antidepressants have much effect on dopamine. Even Bupropion has no effect on dopamine in the brain. Serotonin is a good anxiolytic but SSRIs don't really help much with depression as they don't effect dopamine levels.
Dopamine deficiency has been strongly linked to depression however most drugs which do increase dopamine are not approved for depression. Until SNDRIs or guided psychedelic therapy become available people suffering depression will almost certainly get more relief avoiding antidepressants and finding other solutions such as Mucuna Pruriens or therapy like CBT.
A great video explaining antidepressant. But another question is whether true or not that if you're taking antidepressants for too long, you can't live without it? Or you're dependant on it. Thank you.
I was depressed between 13-16 years old, it was caused by teacher and domestic abuse. I didn't take pills and didn't have any therapy. But as I got more logically advanced, I solved my depression problem. Therefore I think depression is a logic problem and intaking chemicals that will affect neurotransmission is not a good idea.
Did you just suggest that depression is a disease...? diseases are things that have a physical effect on the body an are somewhat easy to diagnosis. Depression is a disorder. you can't tell the physical difference between a person with depression and a person without.
Fuck antidepressants. They turn you into an emotionless and numb zombie. When I was on them, I felt worse. And when you get off of them you can go through hell with withdrawal symptoms. Serotonin isn't a chemical you want to go messing around with, and there can be serious side effects from doing so. Honestly, for anyone struggling with depression, I'd recommend trying lifestyle changes. Proper sleep, diet, exercise, engaging and stress reducing activity, and spending plenty of time with friends and loved ones really helps. Also, no harsh side effects.
It's worked twice for me now and I had no problems getting off the first time. I was left with three really good years until shit came back strong because of my anxiety. People on here are fucking ridiculous with their claims. None of these people went to school for this and assume that their experiences represent a population.
Antidepressants are medications that can help relieve symptoms of depression, social anxiety disorder, anxiety disorders, seasonal affective disorder, and dysthymia, or mild chronic depression, as well as other conditions.
They aim to correct chemical imbalances of neurotransmitters in the brain that are believed to be responsible for changes in mood and behavior.
Depression Medications (Antidepressants)
These are the most commonly prescribed type of antidepressant.
Serotonin and noradrenaline reuptake inhibitors (SNRIs) are used to treat major depression, mood disorders, and possibly but less commonly attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), anxiety disorders, menopausal symptoms, fibromyalgia, and chronic neuropathic pain.
SNRIs raise levels of serotonin and norepinephrine, two neurotransmitters in the brain that play a key role in stabilizing mood.
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants. They are effective in treating depression, and they have fewer side effects than the other antidepressants.
SSRIs block the reuptake, or absorption, of serotonin in the brain. This makes it easier for the brain cells to receive and send messages, resulting in better and more stable moods.
They are called "selective" because they mainly seem to affect serotonin, and not the other neurotransmitters.