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Could a drug prevent depression and PTSD? | Rebecca Brachman

Оценок: 2810 | Просмотров: 136784
The path to better medicine is paved with accidental yet revolutionary discoveries. In this well-told tale of how science happens, neuroscientist Rebecca Brachman shares news of a serendipitous breakthrough treatment that may prevent mental disorders like depression and PTSD from ever developing. And listen for an unexpected — and controversial — twist. TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and much more. Find closed captions and translated subtitles in many languages at http://www.ted.com/translate Follow TED news on Twitter: http://www.twitter.com/tednews Like TED on Facebook: https://www.facebook.com/TED Subscribe to our channel: http://www.youtube.com/user/TEDtalksDirector
Категория: Наука и техника
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Текстовые комментарии (424)
John S (24 дня назад)
Yay! Amazing treatment discovered. Can I have some? No. :(
Liu Bliu (1 месяц назад)
What an AMAZING TED regardless of personal opinions (I’m wise therefore haven’t made my own yet) on the subject!!! Awesome job!!! 👏🏻👏🏻👏🏻👏🏻
Ashley Hundley (1 месяц назад)
CBD oil is an all natural way to treat depression and PTSD. No man made pills. No bad side effects. For more information go to https://www.aisley.myctfocbd.com
Eleni Eliades (2 месяца назад)
Ketamine drips are very expensive, insurance coverage is not available. I was offered to try it however, I declined. It lasts a week to two then you have to go back and get another Ketamine drip { they play music as you lay back in a cushioned chair in the dark } as it takes 20 minutes. Sometimes it doesn't even work, unfortunately you still get charged. It is just too expensive for me $275 - $350 every two weeks.
Gillenz Fluff (3 месяца назад)
What about high serotonin and psychopathy?
John Doe (3 месяца назад)
I've had depression for 20+ years, I've tried a lot of different courses of drugs but after going through all that I'd rather be dead then take anything for depression, outside of exercise, good food, social support and knowing what metal toxicity does to your brain and what poor food and mineral uptake does do your endocrine system. Glyphosate, E.Radiation(wifi/cellphones/smart meters), gut biology. Blood tests don't work you need hair tests. As mad as a hatter-Mercury Autism and Alzheimer's, ADHD linked with aluminium. Copper insomnia, schizo like symptoms Lead -Roman plumbing was lead think about the colosseum. All metal Toxicity causes depression and fatigue and your body can synthesise more of one mineral into toxic levels if it is closest to the mineral you are majorly deficient in on the periodic table. Good luck keep looking, magic pills and big pharma aren't your friend. You can treat a hand held to a burning iron by pumping it full of anesthetic but that won't address the burning iron. Painkillers are fine for a break but you need to research for yourself and take some agency onto your own hands.
Adrian Eyre (4 месяца назад)
That lady is amazing
Hubert Hubert (6 месяцев назад)
Pharmaindustry is like these NGO's helping the fishes and plants dying in a River. Wich is a good job, but theydon!t shut down the factory, poisoning that river. ...Maybe cause they living to good from it?
Wiener Woods (7 месяцев назад)
Ketamine: https://gizmodo.com/ketamine-relieved-suicidal-thoughts-within-hours-in-hos-1821331604
Sarah Barnice (8 месяцев назад)
Fungi- Take nutrients from host more than they give. In a weakend state with no explaination as to what it could be could lead to a stressful state that spirals into depression. As all things do. This is at least what I feel I am experiencing. Especially since I notice that when it feels like I'm treating my dandruff (no room for shame in science) my mood and cognitive ability to make myself feels better impoves. The more severe the dandruff the more difficult it becomes to get out of my depressive state. Sucorro!
Janos Valery Gyuricza (8 месяцев назад)
poor science, full of assumptions.
johnathan clark (9 месяцев назад)
Depression anxiety and ptsd You take illicit drugs like weed. You get caught with it you’ll lose everything. So you talk to your doctors and what they’ll give you for your problems more drugs. I tell them street drugs and pharmacy are the same thing but they’ll say ours are better. To me it’s diet, it’s exercise, it’s our culture, religion, philosophy, the way you communicate your problems to people and coping skills. Doctors and pushers think our problems can be fixed like a headache but depression isn’t a headache. Maybe it’s ok to feel sadness, anxiety and we as individuals have to control our own issues instead of drugs.
Marcus Roizen (11 месяцев назад)
She woke af
Susan Darnell (11 месяцев назад)
I DONT HAVE 2 HOURS A DAY FOR TEDS. TEDS SHOULD BE SHORTER. AND IN TEXT FORM. I READ 1,0000 WORD PER MINUTE. I dont have 2 hours a day for "Teds BLABBERs." Teds should be shorter. And in text form. I read 1,0000 word per minute. to FDA AN DEA? FREAKING MAINSTREAM KETAMINE, BECAUSE THE STREET VERSION CUT WITH FENTANYL + CARFENTANIL. CPR an ER;s saving them. We THE PEOPLE ARE WATCHING YOU. WAKE UP. PLEASE. Even CEOs,12 Steppers, and actors Guild Patients (ie. Philip Seymour Hoffman, and many more Whiteley Huston and her daughter (what tragedies) needed this drug. IT IS THE YEAR OF SUICIDES (still 2017). And ODS (via: Fentanyl's ) I ve seen this video 10 times. The stuff is STILL not mainstream. It has side effects on Newbies and must be a adjusted per patient. Monitored paraprofessional with a flow chart checklist. Even a trusted friend buddy system, like AA.. MDs should not be or cannot be accountable for misuse of Rx's NOTE: LIFE EXPECTANCY IN THE US HAS DROPPED 2 YEARS. BACK TO AGE 78. Since this video first came out. And many more studies, google dr. Nancy Sobiern MD., UCSD, San Diego CA. US. She is also pain management at Scripps Medical center across the same parking lot. SO MANY PATIENTS ARE TOO DEPRESSED TO EVEN GO,CANNOT KEEPP APPTS. THIS LECTURE IS THE TIP OF THE ICEBERG. Double dittos and Roswell's to 'S TO "Rebecca Brachman" for anything. Rebecca Brachman, Do you have anything more we can use? We had a cpr dead person less than 1 mile from my house. 2 days ago.
Art Vein (11 месяцев назад)
They say weed doesn't have side effects but I've watched people lose everything from it including their sober basic reasoning skills
DjDebUsa Bond (1 год назад)
DjDebUsa Bond (1 год назад)
David (1 год назад)
It is also good for "resetting" pain levels after chronic pain. Also it is fun in the bedroom with a person you love. Especially if there are any issues to overcome, like being super shy and getting panic attacks. Ketamax is the best. There are many types of Ketamine, not all brands are equal. The different isomers have different effects. Some brands of K make my pet goat feel like dirt, yet others make him happy. So don't give up at the first brand and look for "Ketamax" with the blue and white label that states "made in Germany", it should only cost $2-$10 for a 10ml bottle(1/2 gram). Also rubbing it on you skin where you have nerve damage really helps with the pain. Also, you can filter out the salt by adding the dried K to anhydrous ethanol(NO WATER!) then filtering it through a fine coffee filter. It will not hurt your goat's nose as much.
Arati Bagal (1 год назад)
Well someone who has suffered from depression or is suffering from depression can truly understand the impact it has on life. True potential of a person goes to waste. It is a really debilitating disease. I know how i have transformed from my pre depression days to now. If there is cure for it and not just symptomatic cure..... a cure for the cause of the disease , it in fact would save lives of people. Not only that but it will enable a human being to reach their own potential.
Kugelblitz (1 год назад)
Yes it's called nutella
doctor shankar (1 год назад)
It's quite obvious that she represents the big pharma. She is not even embarrassed. Depression has to be treated with minimal medication accompanied by psychotherapy. It is psychology which is much more important than medication.
Jacqueline Woo (1 год назад)
maybe thats why i enjoyed ketamine so much as a party kid given that i have the same background. i preferred it over mdma and lsd depending on what was available. not being a jerk, i mean it.
kevin klein (1 год назад)
Zipo214 (1 год назад)
Mm look at that. A Ted talk about a illicit drug. Those of you that do not know, Calipsol is Ketamine. We also know that LSD and MDMA can combat these problems too.
Megan (1 год назад)
It's a business. They won't fix it because it makes them too much money.
Paul (1 год назад)
depression is the leading "disability" over AIDS? No known cures? what she smokin
rahul garg (1 год назад)
she is cute and smart
Hk sabek (1 год назад)
is it a marketing session ?
reen (1 год назад)
anti depression medicines makes you "inappropriately happy"..lol. Excellent presentation on immune vaccines and palliative medicine. But there is also a healer within all of us. Use that to prevent stress and depression
Julia Chernov (1 год назад)
Her voice is sure lovely 😊
oui oui (1 год назад)
you can't fix depression with a pill, it only hides and numbs it. depression is something that you have to fix yourself without medicine if you actually want to get rid of it and not sweep it under the rug
NikkiLove (1 год назад)
YES it's called Opiates.
Suprnovaa (1 год назад)
What about MAPS? MDMA?
YEAR OF THE ROOSTER (1 год назад)
what happens when you ask for help and your doctor lables you as a drug seeker
General Sorrow (3 месяца назад)
You get shut off.
Andy Eccentric (1 год назад)
A jewish woman shilling for big pharma??? Say it ain't so!
Someone (1 год назад)
I do not believe that depression has a cure at least not in the present times, if you say that you had depression and it was cured it was not depression it was something else but I believe that there is still going to be a cure
s B (1 год назад)
Richard no need for a cure. Normal part of the human condition!
soapng2001 (1 год назад)
Drug cannot prevent depression and PTSD, because it is about your thinking, what make you wanna to be depression and PTSD.
Rosumisorimu (1 год назад)
*facepalm* I am shocked at how many ignorant people there are here...I can't believe it's 2017 and there are still people who seriously believe that real clinical depression and PTSD is about "thinking" and not about disrupted brain chemistry. YOUR MENTAL STATE DEPENDS ON YOUR BRAIN! YOUR THOUGHTS ALSO DEPEND ON YOUR BRAIN! YOUR BRAIN IS JUST AS PHYSICAL AS YOUR KIDNEY IS! If someone says, my kidney hurts, you surely won't tell them "it's just about your thinking you don't need to go to a doctor!" won't you??? Dear God, what a ignorant world we live in....it will still take decades before some people get educated....
mena3976 (1 год назад)
Special K. This is a street drug. This is something that can do more harm than good.
MidEnginedSedan (1 год назад)
So blind. You fail to find real solutions, because you think humans are just biological robots.
Nimity Tei (1 год назад)
A drug to prevent depression and PTSD when you actually are depressed or have PTSD? Shouldnt you be fighting the CAUSE, of your mental illness? In my eyes creating an illusionary life, escaping the problem through drug use, is just running from life. Take the red pill.
VEGETADTX (1 год назад)
Do you realize that not ALL depressions have a psychological cause? Do you understand that actually majority of serious clinical cases of Depression come from genetic susceptibility of the brain chemistry to chronically disrupt itself in ways where the parts of the brain involved in emotional regulation, stress, memory, motivation and focus are compromised (some of those areas in the brain are Amygdala, Hippocampus, Nucleus Accumbens etc...). So since the cause of that can not be defined by any other way but - YOU WERE JUST SIMPLY BORN THAT WAY, what do you suggest as the treatment that shoots right at the CAUSE of it? To go back in time and prevent your birth or your genes/brain from forming in a wrong way? Therefore, we need to do what we can do about it, and that's why antidepressants exist, and God bless the researches and scientists...if it wasn't for them we would have been slaughtered already by tons of other diseases that these days seem trivial and easy to treat.
Steven K Harrison (1 год назад)
Hans Dampf (1 год назад)
Great Speech and true for more drugs than just Ketamine - I hope she will suceed. btw - she's the hottest scientist I've seen so far... ^_^
Matilda Bailey (1 год назад)
job identification bench greatly visual guilt fire parental rice.
flblbl (1 год назад)
They already use GHB to treat narcolepsy soooooo why not
Tilius Sodeika (1 год назад)
Of course "mise" knows why they are depressed, they just cannot solve the problems.
Chocolate Warlord (1 год назад)
mmmm, soma
Circe (1 год назад)
Glutamate is also implicated in the development of dementia. We need to be careful if this doesn't increase the risk of developing dementia. But who knows? More research is needed.
General Sorrow (3 месяца назад)
I forget.
Ano Nymous (1 год назад)
drugs will never cure depression. Real life actions will.
Jop Mens (1 год назад)
The great promise may be its metabolite dihydroxynorketamine (it's not the exact full name), which I think is not psychoactive in the way ketamine is "primarily", although the antidepressant doses of K needed are also lower than what you would trip from, but if anything it could help with the image connotations, and it seems like a good idea to isolate the AD activity for AD use.
mcgeufer (1 год назад)
Well that´s late. I saw studys about Ketamin as anti depresant about 10 years ago in Europe. Why does it take so long ?
Fran Roman (1 год назад)
Lauren Fry (1 год назад)
This vaccine won't be profitable. Pharmaceutical companies make so much off SSRI's. They won't market something that will make their other products that bring them billions of dollars obsolete.
hocus pocus (1 год назад)
*Drugs show you that your mind is largely a chemical reaction*. Hormones and chemicals can and do change the way you feel, your behavior, and even the way you think. People on hard drugs feel the world is perfect when they are high, but the next day they feel the withdrawals. Overcoming depression and PTSD, can only be done by changing the state of your mind permantly. *The medicine to overcome any bad mindstate permantly is the just recently revealed ultimate truth of life*. The *Truth* explains the big picture of life in every facet, it explains the nature of everything, including the real *truth* about the nature of the mind and the key to overcome it. Google *truthcontest and read the present*
theUglyManowar (1 год назад)
only point out as much is a point they r trying to make in an easily apparent way. The nerve of some people. If I wanted legibility I would have gone to school!
ben belt (1 год назад)
hocus pocus bold letters don't makes your point any more or less valid
Trippy Giphy (1 год назад)
Yea, but people want a quick fix... so sad..
Eliot Brun (1 год назад)
Blame error form patient abuse president sir.
Treasuretrails RS (1 год назад)
Yeah it's called Marijuana
OpiatedBliss (1 год назад)
well, that's the best excuse I've seen to do some K
Kalenz (1 год назад)
No cures for PTSD? Of course there is. Its called hugs. Lots of hugs
PS (1 год назад)
It's getting old listening to scientists mock how stupid scientists were in the past and flaunt arrogantly how impeccable and perfect their knowledge is in the present. The fact that these people still think the solution rests in coming up with the next best pill to control for the side effects of the last pill, is all the proof you need that they're still in the stone age when it comes to healing.
Ryan Graham (1 год назад)
Great TED Talk! Well done and well said...
bigfootpegrande (1 год назад)
What about turning all resources towards minimizing preventable stress and trauma, such as wars and refugees?
Benjamin Connell (1 год назад)
I love that 3 of the top 4 posts on this thread are jokes about the drug being a recreational drug "Yes, it's called mdma", "It's called Weed", "yes its called lsd". Well the joke's on them because if any of them had actually watched this video to the end then they'd know that the twist is it's actually called Special K!
Stefan Podolczuk (1 год назад)
this idea has been spread already, unsuccessfully in many cases
Starlyn Kunz (1 год назад)
To prevent or cure PTSD would be amazing, But does this change you as a person? Does it numb you in a way if that makes sense?
Pixie May (1 год назад)
yelloworangered (1 год назад)
Why do TED talkers so sound smug?
HARNESS84 _ (1 год назад)
MDMA helped me talk about my issues when i was younger. it worked great. the world is so closed minded when it comes to drugs and their true power. i have never heard of anyone going out on the town and getting into a fight on MDMA, but alcohol which is legal everywhere causes drink driving,domestic violence and deaths everywhere......such a great society we live in
Chris Needham (1 год назад)
Stephen Smith (1 год назад)
I love where this woman's heart is, but the fact that a para-vaccine as she proposes will, basically eliminate or at best drastically reduce an existing massive revenue stream for those companies who have an invested interest, not to mention a further interest in her product/concept failing (for any reason out side of science... I'm sure such failure does have a price to ensure same). While not wanting to sound like a conspiracy nut... the Petrochemical Industry is a glaring light-bulb of similarity!
Richard Sbattella (1 год назад)
Ketamin is probably the Prodrug for the antidepressant that metabolizes from it: Hydroxynorketamin
Richard Sbattella (1 год назад)
It seems that AMPA Rezeptors are more involved in depression than the NMDA Rezeptor wich is affected By Ketamin
Max Robert (1 год назад)
Anyone who uses unperscribed drugs are idiots.
Damjan Dobrila (1 год назад)
M G (1 год назад)
How stupid is everyone, even the title screams stupid.. Fail uploader - I'm going to unsubscribe [from stupid]..!
Austin Bradley (1 год назад)
eSKAone (1 год назад)
People will use more and more drugs.
eSKAone (1 год назад)
The mind is a symphony of thousands of substances and physiological mechanisms. There is no key substance. I don't think drugs are the answer. People need a purpose.
Randy Randerson (1 год назад)
7:00 except for MDMA which fully cures PTSD and cannabis which helps with depression and both always have fore decades/centuries now...
David (1 год назад)
Excellent presentation!
Jacob Fort (1 год назад)
It was actually terrible. There were obvious flaws, she went off topic more than once and for up to 2 and half minutes, and she's just promoting another brain killing drug to help big pharmaceuticals make money.
J Attitude (1 год назад)
You say that the cost is trillions dollars is there a way that companies that help prevent this kind of disease can get a little tax deduction? Ore like in Germany where they get tree weeks of at a spa to recover if they have symptoms like the ones you discussed?
Adrien Perié (1 год назад)
9 times out of 10 Depression is only a serious illness if you start taking meds for it.
VEGETADTX (1 год назад)
I am really interested in how did you get to that conclusion? Would you mind sharing the statistical research you've done to conclude something like that? I've used medication for my depression, anxiety and other symptoms in the past and it served it's purpose (at least for some symptoms). I no longer take any medications and I've been stable for few years now, so I'm pretty sure I would never say that my depression became serious because of the meds, it was serious itself from the very beginning, and now it's gone. I think people should think more before being so much cynical about everything and anything, especially about pharmaceutical industry and health care...without them humanity would cease to exist.
Jacob Fort (1 год назад)
It's gotta be serious if you're trying to find drugs for it.
Young Padawan (1 год назад)
Depression is just Unhappiness With Your Own Life. Don't get fooled by BS. Have a nice day.
Sheev Palpatine (21 день назад)
Young Padawan mmmm that’s wrong my dude. It is so much more than that it is a disease.
Anthony (1 год назад)
I'm pretty sure the outbreak of mental illness in the US is from drugs and pollution in out water. She forgot to mention because of this re-purposing, big pharma gets to re-copyright these drugs , making them cost more and more.
Sam'sSunmetaphysiCAL. (1 год назад)
Marijuana is going to crush the company that paid you to speak, you may have the ground pulled from under you, nothing personal.
xApemanx (1 год назад)
too bad being high has bad side effects
Tas (1 год назад)
*This* is the TED I subscribed for, not SJW bullshit.
Jacob Fort (1 год назад)
I agree with the SJW bullshit, but seriously? This video was terrible. I have deep depression, had it for years, and she obviously doesn't know what she's talking about.
KLS- 95 (1 год назад)
Animal testing. SMH.
gay (1 год назад)
Sujin Lee (1 год назад)
What doctors need to stop doing is overprescribing antidepressants cos there's a whole heap of health problems that cause depression-like symptoms that antidepressants will not fix. An underactive thyroid? undiagnosed eating disorder? low vitamin d? low b12? low iron? high cortisol? all of these can be related to each other but simply handing out SSRIS like candy is not gonna fix the issue. I learnt that the hard way. Of course, people suffering from low serotonin related depression benefit greatly from SSRIS but y'all (doctors and patients) need to consider other causes too!
sheffair1 (1 год назад)
Great talk - very interesting 👍
Tito BunkN (1 год назад)
there's an all natural alternative called Marijuana. Seriously.
Faiz idju (1 год назад)
She is extremely hot to me
PTHaze (1 год назад)
Maulrus (1 год назад)
Worth a google. Also known as Ketamine........
Jonas Karlsen (1 год назад)
If 1 out of 4 experience depression then maybe its not the people Who are sick. Maybe its the system that is sick.
Scroto Bagging (3 месяца назад)
3rd world coutries have less depression... Welcome to the machine..
theUglyManowar (1 год назад)
They already know that it's a stress induced Industrial age epidemic. Along with cancer and Diabetes. We know that when poverty levels drop that many issues like crime show relief. So addressing such stress factors will B great. But I liked how she stressed that the problem ends up being chronic for many sufferers! 40 years for myself ( with a 12 year interim where I thought I was home free )
Jonas Karlsen (1 год назад)
But thats where we need to think in another mindset. If people are told that there condition is cronicle then it becomes cronicle to them. How you persive yourself affects your mental healh on a greater scale. Drugs should be a last resort supplementet with therapy. If you still se yourself as depressed when you take drugs then it is still there when you stop taking them.
Jop Mens (1 год назад)
I'd say it is important to differentiate chronic sadness from depression. Like you suggest, sadness is a healthy response to bad things happening, but the point is that with depression you are sad even with good things happening. In the model of this video, that would be where the mouse has nothing to fear anymore but still won't really come out. You could call that micro-traumatized though I guess. Animal models can be pretty imperfect.
Emanuele Santanche (1 год назад)
We are the first adults to handle the generation gap through the wholesale drugging of our children. We may be guaranteeing that future generations will be relatively devoid of people who think creatively, raise painful questions, generate productive conflicts, or lead us to new spiritual and political insights. — Dorothy Rowe, Beyond Fear We regard the medical model as an extremely inappropriate model for dealing with psychological disturbances. The model that makes more sense is a growth model or a developmental model. In other words we see people as having a potential for growth and development and that can be released under the right psychological climate. We don't see them as sick and needing a diagnosis, a prescription and a cure; and that is a very fundamental difference with a good many implications. — Carl Rogers She says: "we might be able to protect people who are predictably at risk against stress-induced disorders like depression and ptsd" -- what about loving them? what happened to love? We used it to heal the pain of distressed people for thousands of years and it worked! Freedom is the best antidepressant in the world. Those who want us to be slaves so that they can exploit us prefer us to take drugs of course instead of giving us freedom. Never take these drugs. They are only used to shut us up. If education was based on freedom and absence of fear instead of violence, our childhood would be our antidepressant. It's that the psychotics who rule the world want us scared.
darkskevin (1 год назад)
a drug won't prevent depression because depression is cause by a person's history a drug will just cause maybe addiction and just make a artificial hapiness on a person because they manipulate the brain and not the depression's cause
Bunghole Burglar stealing YO sh!t (1 год назад)
the mind is far too complex
Pakislav (1 год назад)
I need to go to a vet.
KROOL (1 год назад)
I wanna try Ketamine.
Don Honas (1 год назад)
Still a lot of hypotheses and unknown long-term consequences. Taking a psychoactive drug as prevention feels also really problematic. But it would definitely be worth to do further study on.
Don Honas (1 год назад)
Thanks for the tip!
KROOL (1 год назад)
¸Google doctor Carl Hart.
FancyThatBumNow (1 год назад)
15:50 what a twist! great talk :)
Cook The Book (1 год назад)
why not accept a natural life?? the thing about drugs is once your body gets use to it you have to keep upping the dosage and that can kill your natural endorphins meaning once you stop the drug completely it'll take you forever or you might never experience natural happiness again.. the cure for depression and ptsd is education and living a healthy life style! a better you = a better life...
Alice Walker (1 год назад)
ReZShot I am an emergency service worker who practices yoga and meditation, runs, eats well, has good social support, regularly sees a therapist for check ups... In other words who is privileged enough to be able to look after my own health "naturally" .... I still developed PTSD and subsequent depression. One of the beliefs I'd absorbed that harmed me the most was "if you tried harder to look after yourself naturally you'd stop being so depressed and won't need medication" it literally cost me over a year of my life. Sometimes mood disorders can can be improved to a point of wellness by "natural" means but sometimes they can't. Sometimes people don't have the luxury or ability of investing the time, energy and money it takes. Mental health medication is absolutely vital. The "natural is better" narrative can do as much harm as help. Obviously it'd be awesome to live in a world that wasn't so traumatic that so many of us develop mental illness as a result, but that kind of change takes generations and if a quarter of us are worn out fighting for our sanity it makes effective and lasting change harder. I think this is a great talk and I fully support what she's saying and better drugs for mental health care.

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